Now showing 1 - 10 of 17
  • Publication
    Preliminary studies on antimicrobial activity of extracts from aloe vera leaf, citrus hystrix leaf, zingiber officinale and Sabah snake grass against bacillus subtilis
    Herbal plants have several potential antimicrobial activities either as antifungal or antibacterial to fight against the disease and pathogen that attack the plants. The extractions of the Aloe vera leaf, Citrus hystrix leaf, Zingiber officinale rhizome and Sabah snake grass were selected in this study to fight against Bacillus subtilis. B. subtilis is a Gram-positive bacterium, rodshaped and catalase-positive that lives on decayed organic material. It is known as Gram-positive bacteria because of its thick peptidoglycan and would appear purple when subjected to Gram test. This species is commonly found in the upper layers of the soil, in meat or vegetables, in pastry, cooked meat, in bread or poultry products. The extracts of Sabah Snake Grass found to be most effective than A.vera leaf, Z. officinale, and C. hystrix against the B. subtilis.
  • Publication
    Glucose production from sugarcane bagasse by two stages chemical pretreatment & hydrolysis
    (IOP Publishing, 2020)
    Nurul Syiffa Husna Che Roslan
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    The aim of this work was to produce glucose from sugarcane waste. It consists of high cellulose, hemicellulose and lignin which enables to be converted into a glucose production. Three conditions of acid hydrolysis was measured by using One Factor at a Time (OFAT) which consist of sulphuric acid concentration, retention time and temperature. The highest yield and optimum conditions from OFAT parameters were further continue with the enzymatic hydrolysis by using Central Composite Design (CCD). The optimization of enzymatic hydrolysis for the conversion of cellulose to glucose was conducted by using three independent variables which were pH, temperature and enzyme dosage. Based on the data of Design of Expert (DOE) software from optimization of enzymatic hydrolysis, the optimum glucose production was determined by using Dinitrosalicylic Acid Reagent (DNS) method.
  • Publication
    Thermoplastic starch hybrid biocomposite films with improved strength and flexibility produced through crosslinking via carboxylic acid
    Thermoplastic starch (TPS) suffers from its intrinsic low mechanical strength and high brittleness due to its strong hydrogen bonding and low chain mobility. The conventional way to crosslink the TPS film can improve the strength and stiffness of the films, but usually reduces the flexibility of the film, and increases its brittleness. In this study, the incorporation of the hybrid nanofiller [1 wt% nanocellulose (C) and 4 wt% nano bentonite (B)] into the TPS proved to improve greatly the films’ strength and flexibility. The hybrid nanofillers with ratio 4B:1C was incorporated into the crosslinked thermoplastic corn starch (CR-TPCS) film to increase the its flexibility and toughness and produced a high mechanical strength fully biodegradable film. Two different aqueous carboxylic acids: citric acid (CA) and tartaric acid (TA) with different pH values (2,4,6) as the green crosslinker were employed. Substantial increase of tensile strength (3.98 to 9.17 MPa), Young’s modulus (9.10 to 46.30 MPa) and elongation at break (55.2 to 135.7%) was observed for the CA- 4B1C/pH2 films compared to the CR-TPCS films. The melting temperature (Tm) of the CA-4B1C/pH2 improved compared to the TPCS/4B1C (un-crosslinked) film due to its crosslinking effect. Meanwhile, the CA-4B1C films exhibited the highest degree of substitution and di-esterification with the lowest swelling and water solubility properties due to the formation of a special “bridge” structure between the CA, nanocellulose and plasticizer. The “bridge” structure developed between the TPCS chains serves as the toughener to motivate higher chain stress relaxation and load endurance. The crosslinked “bridge structure” also proved to effectively reduce the retrogradation phenomenal in the TPCS films. This combination method of hybridization and crosslinking is an efficient, low cost, and environmentally friendly technique to overcome the low flexibility and brittleness problem of the TPS based packaging film.
      2  36
  • Publication
    New Development Quantification Methods for Salt Iodine and Urinary Iodine Using Microfluidics Based Nanotechnology
    ( 2020-03-18)
    Nur Hulwani Ibrahim
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    ; ; ; ;
    Muhammad Nur Afnan Uda
    In Malaysia, the first Iodine Deficiency Disorders (IDD) survey was conducted in 1996 and it was discovered that Peninsular Malaysia did not have IDD problem until latter studies showed goitre occurrence of 34.7% in Hulu Langat district and urinary iodine lower than the adequate level of (100-199 ug/L) in Perak and Pahang states (Selamat et al., 2010). Baseline and periodical sampling of children and pregnant woman urine and imported salt commodities for the consumption of the population is mandatory for iodine measurement. Thus, development of quantitative methods of measurement of salt and food iodine is crucial for implementation of the USI program nationwide. In this study, interdigitated electrode (IDE) biosensor, a rapid, sensitive and selective method has been developed to determine the iodine content in both urine and salt. This method includes functionalization and silanization step using 3-aminopropyl triethoxysilane (APTES). The I-V characterization of IDE biosensor was performed using (Keithley 2450), Kickstart software and Probestation. It measures the amount of current flow through IDE which is directly proportional to the concentration of iodine in both urine and salt. Hence, IDE biosensor is proven to be a rapid, selective, sensitive method and can be developed as a new nanotechnology for the elimination of Iodine Deficiency Disorders (IDD) among children and pregnant woman.
      44  1
  • Publication
    Key features of additive manufacturing: A review
    This work reviews the key features and capabilities of additive manufacturing, which include the fundamental of additive manufacturing followed by types of additive manufacturing technologies. Advantages and limitation of additive manufacturing is discussed and the emergence of additive manufacturing in industrial revolution 4.0 is presented. Economy benefits through the additive manufacturing showing beneficial potential.
      34  1
  • Publication
    Optimization of Pretreatment and Enzymatic Hydrolysis of Spent Coffee Ground for the Production of Fermentable Sugar
    The aim of this work was to optimize the condition of pretreatment and enzymatic hydrolysis for high yield of sugar production of spent coffee ground (SCG). Acid and alkaline pretreatment method were compared and the method with more sugar produced was selected. Response surface methodology was use for the analysis of conditions such as concentration of alkali, temperature and weight of SCG. The optimized condition obtained was 0.5% (v/v) of alkali, temperature of 100°C and 5% (w/v) of SCG. Enzymatic hydrolysis was carried out after the optimized condition of alkaline pretreatment. The conditions were pH, temperature and enzyme dosage. The optimized condition obtained was at pH 4.8, 0.01 ml of enzyme and temperature of 55°C.
      1  18
  • Publication
    Recent advances in synthesis of graphite from agricultural bio-waste material: a review
    Graphitic carbon is a valuable material that can be utilized in many fields, such as electronics, energy storage and wastewater filtration. Due to the high demand for commercial graphite, an alternative raw material with lower costs that is environmentally friendly has been explored. Amongst these, an agricultural bio-waste material has become an option due to its highly bioactive properties, such as bioavailability, antioxidant, antimicrobial, in vitro and anti-inflammatory properties. In addition, biomass wastes usually have high organic carbon content, which has been discovered by many researchers as an alternative carbon material to produce graphite. However, there are several challenges associated with the graphite production process from biomass waste materials, such as impurities, the processing conditions and production costs. Agricultural bio-waste materials typically contain many volatiles and impurities, which can interfere with the synthesis process and reduce the quality of the graphitic carbon produced. Moreover, the processing conditions required for the synthesis of graphitic carbon from agricultural biomass waste materials are quite challenging to optimize. The temperature, pressure, catalyst used and other parameters must be carefully controlled to ensure that the desired product is obtained. Nevertheless, the use of agricultural biomass waste materials as a raw material for graphitic carbon synthesis can reduce the production costs. Improving the overall cost-effectiveness of this approach depends on many factors, including the availability and cost of the feedstock, the processing costs and the market demand for the final product. Therefore, in this review, the importance of biomass waste utilization is discussed. Various methods of synthesizing graphitic carbon are also reviewed. The discussion ranges from the conversion of biomass waste into carbon-rich feedstocks with different recent advances to the method of synthesis of graphitic carbon. The importance of utilizing agricultural biomass waste and the types of potential biomass waste carbon precursors and their pre-treatment methods are also reviewed. Finally, the gaps found in the previous research are proposed as a future research suggestion. Overall, the synthesis of graphite from agricultural bio-waste materials is a promising area of research, but more work is needed to address the challenges associated with this process and to demonstrate its viability at scale.
      15  22
  • Publication
    Synthesis and characterization of reduced graphene oxide using the aqueous extract of Eclipta prostrata
    ( 2020-08-01)
    Chuah Regnant
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    ;
    Anbu P.
    ;
    ; ;
    Lakshmipriya Thangavel
    In this study, biological deoxygenation of graphene oxide (GO) using an Eclipta prostrata phytoextract was performed via the infusion method. The presence of oxide groups on the surface of graphene and removal of oxides groups by reduction were characterized through morphological and structural analyses. Field emission scanning electron microscopy images revealed that the synthesized GO and rGO were smooth and morphologically sound. Transmission electron microscopy images showed rGO developing lattice fringes with smooth edges and transparent sheets. Atomic force microscopy images showed an increase in the surface roughness of graphite oxide (14.29 nm) compared with that of graphite (1.784 nm) due to the presence of oxide groups after oxidation, and the restoration of surface roughness to 2.051 nm upon reduction. Energy dispersive X-ray analysis indicated a difference in the carbon/oxygen ratio between GO (1.90) and rGO (2.70). Fourier-transform infrared spectroscopy spectrum revealed peak stretches at 1029, 1388, 1578, and 1630 cm−1 for GO, and a decrease in the peak intensity after reduction that confirmed the removal of oxide groups. X-ray photoelectron microscopy also showed a decrease in the intensity of oxygen peak after reduction. In addition, thermogravimetric analysis suggested that rGO was less thermally stable than graphite, graphite oxide, and GO, with rGO decomposing after heating at temperatures ranging from room temperature to 600 °C.
      3  13
  • Publication
    A review on additive manufacturing in bioresorbable stent manufacture
    Vascular injury and disease as well as cardiac and cardiovascular diseases have been a serious threat to human life and health today. Stents implantation have been the primary treatment for vascular diseases. Polymeric bioresorbable stents manufactured with 3D printer is newly emerged. This work review the bioresorbable stents and the utilization of additive manufacturing in bioresorbable stent manufacture.
      2  37
  • Publication
    Malaria Parasite Diagnosis Using Computational Techniques: A Comprehensive Review
    Malaria is a very serious disease that caused by the transmitted of parasites through the bites of infected Anopheles mosquito. Malaria death cases can be reduced and prevented through early diagnosis and prompt treatment. A fast and easy-to-use method, with high performance is required to differentiate malaria from non-malarial fevers. Manual examination of blood smears is currently the gold standard, but it is time-consuming, labour-intensive, requires skilled microscopists and the sensitivity of the method depends heavily on the skills of the microscopist. Currently, microscopy-based diagnosis remains the most widely used approach for malaria diagnosis. The development of automated malaria detection techniques is still a field of interest. Automated detection is faster and high accuracy compared to the traditional technique using microscopy. This paper presents an exhaustive review of these studies and suggests a direction for future developments of the malaria detection techniques. This paper analysis of three popular computational approaches which is k-mean clustering, neural network, and morphological approach was presented. Based on overall performance, many research proposed based on the morphological approach in order to detect malaria.
      9  32