Muhammad Nur Aiman Uda
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Preferred name
Muhammad Nur Aiman Uda
Official Name
Muhammad Nur Aiman, Uda
Alternative Name
Uda, M. N.A.
Aiman Uda, Muhammad Nur
Uda, M. N.A.
Main Affiliation
Scopus Author ID
55984680000
Researcher ID
V-7751-2019

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  • Publication
    Gold Nanoparticles Enhanced Electrochemical Impedance Sensor (EIS) for Human Papillomavirus (HPV) 16 Detection E6 region
    ( 2020-07-09)
    Amrul Muhadi A.S.
    ;
    Nor Azizah Parmin
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Rejali Z.
    ;
    Afzan A.
    ;
    Muhammad Nur Afnan Uda
    ;
    Muhammad Nur Aiman Uda
    ;
    Hong V.C.
    The persistent infection by high risk HPV is a necessary but not sufficient cause of this cancer which develops over a long period through precursor lesions which can be detected by electrochemical impedance sensor. The HPV driven molecular mechanisms underlying the development of cervical lesions have provided a number of potential biomarkers for both diagnostic and prognostic use in the clinical management of women with HPV related cervical disease and these biomarkers can also be used to increase the positive predictive value of current methods. The most influential methods for the detection and identification of HPV using gold nanoparticle (GNP) included electrochemical impedance sensor will visit their sensitivity, selectivity and characteristic detection on synthetic target which are complement of the DNA, non-complement of the DNA and mismatch of the DNA. In difference concentration of synthetic target, which stage can get the exactly value to determine the HPV in strain 16 was evaluated in this research studies.
  • Publication
    Preliminary studies on antimicrobial activity of extracts from aloe vera leaf, citrus hystrix leaf, zingiber officinale and Sabah snake grass against bacillus subtilis
    ( 2018)
    Muhammad Nur Aiman Uda
    ;
    Subash Chandra Bose Gopinath
    ;
    Nur Hulwani Ibrahim
    ;
    Mohd Khairul Rabani Hashim
    ;
    Nuradibah Mohd Amer
    ;
    Midhat Nabil Ahmad Salimi
    ;
    Tan Ewe Shen
    ;
    Ong Yee Fen
    ;
    Maisara Azad Mat Akhir
    ;
    Uda Hashim
    Herbal plants have several potential antimicrobial activities either as antifungal or antibacterial to fight against the disease and pathogen that attack the plants. The extractions of the Aloe vera leaf, Citrus hystrix leaf, Zingiber officinale rhizome and Sabah snake grass were selected in this study to fight against Bacillus subtilis. B. subtilis is a Gram-positive bacterium, rodshaped and catalase-positive that lives on decayed organic material. It is known as Gram-positive bacteria because of its thick peptidoglycan and would appear purple when subjected to Gram test. This species is commonly found in the upper layers of the soil, in meat or vegetables, in pastry, cooked meat, in bread or poultry products. The extracts of Sabah Snake Grass found to be most effective than A.vera leaf, Z. officinale, and C. hystrix against the B. subtilis.
  • Publication
    Potentials of MicroRNA in Early Detection of Ovarian Cancer by Analytical Electrical Biosensors
    ( 2022-01-01)
    Nor Azizah Parmin
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Nadzirah S.
    ;
    Salimi M.N.
    ;
    Voon Chun Hong
    ;
    Muhammad Nur Aiman Uda
    ;
    Muhammad Nur Afnan Uda
    ;
    Rozi S.K.M.
    ;
    Rejali Z.
    ;
    Afzan A.
    ;
    Azan M.I.A.
    ;
    Yaakub A.R.W.
    ;
    Hamzah A.A.
    ;
    Dee C.F.
    The importance of nanotechnology in medical applications especially with biomedical sensing devices is undoubted. Several medical diagnostics have been developed by taking the advantage of nanomaterials, especially with electrical biosensors. Biosensors have been predominantly used for the quantification of different clinical biomarkers toward detection, screening, and follow-up the treatment. At present, ovarian cancer is one of the severe complications that cannot be identified until it becomes most dangerous as the advanced stage. Based on the American Cancer Society, 20% of cases involved in the detection of ovarian cancer are diagnosed at an early stage and 80% diagnosed at the later stages. The patient just has a common digestive problem and stomach ache as early symptoms and people used to ignore these symptoms. Micro ribonucleic acid (miRNA) is classified as small non-coding RNAs, their expressions change due to the association of cancer development and progression. This article reviews and discusses on the currently available strategies for the early detection of ovarian cancers using miRNA as a biomarker associated with electrical biosensors. A unique miRNA-based biomarker detections are specially highlighted with biosensor platforms to diagnose ovarian cancer.
  • Publication
    Production and characterization of graphene from carbonaceous rice straw by cost-effect extraction
    ( 2021-05-01)
    Muhammad Nur Aiman Uda
    ;
    Subash Chandra Bose Gopinath
    ;
    Uda Hashim
    ;
    Halim N.H.
    ;
    Nor Azizah Parmin
    ;
    Muhammad Nur Afnan Uda
    ;
    Anbu P.
    This paper describes the synthesis of graphene-based activated carbon from carbonaceous rice straw fly ash in an electrical furnace and the subsequent potassium hydroxide extraction. The produced graphene has a proper morphological structure; flakes and a rough surface can be observed. The average size of the graphene was defined as up to 2000 nm and clarification was provided by high-resolution microscopes (FESEM and FETEM). Crystallinity was confirmed by surface area electron diffraction. The chemical bonding from the graphene was clearly observed, with –C=C– and O–H stretching at peaks of 1644 cm−1 and 3435 cm−1, respectively. Impurities in the graphene were found using X-ray photoelectron spectroscopy and energy dispersive X-ray spectroscopy. The measured size, according to zeta-potential analysis, was 8722.2 ± 25 nm, and the average polydispersity index was 0.576. The stability of the mass reduction was analyzed by a thermogravimetric at 100 Â°C, with a final reduction of ~ 11%.
  • Publication
    Voltammetric DNA Biosensor for Human Papillomavirus (HPV) Strain 18 Detection
    ( 2020-07-09)
    Mhd Akhir M.A.
    ;
    Nor Azizah Parmin
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Rejali Z.
    ;
    Afzan A.
    ;
    Muhammad Nur Aiman Uda
    ;
    Muhammad Nur Afnan Uda
    ;
    Voon Chun Hong
    This research was developed to focus on the study of the voltammetric DNA biosensor for the detection of HPV strain 18. In this research, electrical DNA biosensor was expected to detect HPV strain 18 more efficiently by using electrical characterization. In this project, device inspection was conducted to make sure the functional of the gold interdigitated electrode (IDE) by using Scanning Electron Microscope (SEM). 3-Aminopropyl Triethoxysilane (APTES) solution was used for the process of surface modification to form the amine group on the surface of the device to facilitate the attachment of the DNA probe. In this project, synthetic DNA sample and DNA from the saliva of several Biosystems Engineering students were used as the target DNA. The current-voltage (I-V) electrical characterization was conducted to detect the presence of HPV strain 18 in both DNA samples. As the results, perfect alignment between the electrodes on the IDE was detected under SEM. Surface modification of the biosensor successfully conducted which is the covalent bond between APTES and DNA probe increase the electrical. Synthetic DNA shows the presence of HPV strain 18 while there was no HPV strain 18 detected in the DNA from saliva samples.
  • Publication
    Biosensor diagnostic system for selective detection of RNA Covid-19
    ( 2024-03-21)
    Muhammad Nur Aiman Uda
    ;
    Uda Hashim
    ;
    Muhd Nur Afnan Uda
    An outbreak of severe acute respiratory coronavirus 2 (SARS-CoV-2) infection occurred in Wuhan, Hubei Province, China and spread across China and beyond. WHO officially named the disease caused by the novel coronavirus as Coronavirus Disease 2019 (Covid-19). Features included pyrexia, radiological signs or acute respiratory distress, reduced or normal white blood cells, lymphopenia, and failure to resolve over 3 to 5 days of antibiotic treatment. This paper describes ultra-selective and rapid to detect the electrical signal generated by the biosensor that converts the biological reaction into an electrical signal and can make early RNA Covid-19 detection. As a step in preparing the biosensor, silanization with (3-Aminopropyl) Triethoxysilane (APTES), immobilization of RNA Covid-19 Probe were used. Then, the biosensor was hybridized to perform selectivity measurement using complementary and non-complementary RNA Covid-19 target.
  • Publication
    The effects of interactional justice and OCB on burnout: Empirical evidences among housemen in Malaysia public hospital
    ( 2021-05-03)
    Sulaiman M.K.
    ;
    Ummi Naiemah Saraih
    ;
    Sakdan M.F.
    ;
    Aminudin Anuar
    ;
    Muhammad Aizat Abu Bakar
    ;
    Muhammad Nur Aiman Uda
    ;
    Asyraf Hakimi Abu Bakar
    This study investigates the effect of interactional justice (IJ) and organizational citizenship behaviour (OCB) on burnout (BO) among housemen in Malaysia Public Hospital. This study involve 15 urban hospital in Malaysia. Quantitative method was used in the study to analyse the questionnaire. The questionnaire will distribute to the 800 housemen in 15 urban public hospital in Malaysia. The questionnaire will analyze by using PLS-SEM statistical tool. From the analyze the hypothesis are accepted and significant. The IJ and OCB can reduce the value of BO among housemen in public hospital. The information based on this study will be a valuable guide to the Ministry of Health (MoH) in and decrease the level of burnout among housemen in Malaysia. The hospital management also can use the information based on the study to upgrade the policy and standard operating procedure (SOP) towards the management of the housemen. Also, this study can be the basis to help the Malaysian housemen to identify the causes of burnout and improve their perspectives upon this issue. Not only that, knowing the dimensions of burnout and its causes can create a positive vibe in the medical environment, particularly among the ministry, hospital management, housemen, and patients.
  • Publication
    Extraction of Spear Grass (Imperata Cylindrica) as Pro-Oxidant In polymer blends
    ( 2018)
    Nuradibah Mohd Amer
    ;
    N. A. Abdul Halim
    ;
    K.F. Kasim
    ;
    S.T. Sam
    ;
    H.I. Zulhaimi
    ;
    Muhammad Nur Aiman Uda
    Packaging material such as plastic bags is one of the main factors that contribute to the environmental pollution due to slow degradation. The usage of metal oxide as pro-oxidant has been proven to accelerate the degradation of these materials, but the excessive usage of this pro-oxidant will be harmful to the human body. Therefore, in this research, spear grass is investigated to be used as natural based pro-oxidant that can increase the degradation rate of the polymers. In terms of that, spear grass is extracted by using pressurized hot water extraction (PHWE) to obtain the metal element such as zinc (Zn) and ferum (Fe). PHWE is using water as a solvent which is highly favourable due to non-toxicity and non-flammable characteristics that make it easy to handle. Box-Behnken design is used to optimize the temperature, extraction time, and sample-to-solvent ratio to get the maximum amount of Zn and Fe concentration from the extracted spear grass. As a conclusion, the leaf of spear grass contributed the highest amount of Zn and Fe concentration. The highest amount of Zn and Fe concentration is achieved at 150 °C, 20 minutes, and 3 g of sample to 45 ml of water.
  • Publication
    Distinct Detection of Ganoderma Boninense On Metal Oxides-Gold Nanoparticle Composite Deposited Interdigitated Electrode DNA sensor
    ( 2021-12-14)
    Thivina V.
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Adilah Ayoib
    ;
    Nordin N.K.S.
    ;
    Muhammad Nur Aiman Uda
    ;
    Muhammad Nur Afnan Uda
    Oil palms suffer severe losses due to Ganoderma boninense infection that causes Basal Stem Rot (BSR). The available detection measuring the severity of BSR disease have not proved satisfactory output. Due to the influence of oil palm industry in country's economy, effective and efficient means of diagnostic measure is mandatory. Among the available diagnostic tools, biosensors were redeemed to yield the most rapid and selective results. To overcome the current issues, herein Interdigitated Electrode (IDE) electrochemical DNA biosensor to detect Ganoderma boninense was successfully designed and fabricated by thermal deposition. Lift-off photolithography fabrication process was applied followed by the surface chemical functionalization via seed deposition. Zinc Oxide (ZnO) and Titanium Dioxide (TiO2) were overlaid and the functionalized metal oxides IDE surfaces were used to detect DNA sequence complementation from Ganoderma boninense. Furthermore, gold nanoparticles were doped to increase the surface to volume ratio and enhance biocompatibility. Characterizations were made by validating the sensor's topology characteristics and electrical characteristics. From the results recorded, it has been justified that IDE with ZnO doped with gold nanoparticles surface serves as an excellent DNA sensor for the detection of Ganoderma boninense with a remarkable current of 290 nA and 176 nA for immobilization and hybridization respectively.
  • Publication
    Production and characterization of silica nanoparticles from fly ash: conversion of agro-waste into resource
    ( 2021-01-01)
    Muhammad Nur Aiman Uda
    ;
    Subash Chandra Bose Gopinath
    ;
    Uda Hashim
    ;
    Halim N.H.
    ;
    Parmin N.A.
    ;
    Muhammad Nur Afnan Uda
    ;
    Anbu P.
    A chemical method to synthesize amorphous silica nanoparticles from the incinerated paddy straw has been introduced. The synthesis was conducted through the hydrolysis by alkaline-acidic treatments. As a result, silica particles produced with the sizes were ranging at 60–90 nm, determined by high-resolution microscopy. The crystallinity was confirmed by surface area electron diffraction. Apart from that, chemical and diffraction analyses for both rice straw ash and synthesized silica nanoparticles were conducted by X-ray diffraction and Fourier-transform infrared spectroscopy. The percentage of silica from the incinerated straw was calculated to be 28.3. The prominent surface chemical bonding on the generated silica nanoparticles was with Si–O–Si, stretch of Si–O and symmetric Si–O bonds at peaks of 1090, 471, and 780 cm−1, respectively. To confirm the impurities of the elements in the produced silica, were analyzed using X-ray photoelectron spectroscopy and energy dispersive X-ray spectroscopy. The stability of silica nanoparticles was investigated using thermogravimetric analysis and zeta potential. The measured size from zeta potential analysis was 411.3–493 nm and the stability of mass reduction was located at 200 °C with final amount of mass reduced ∼88% and an average polydispersity Index was 0.195–0.224.