Humans' and the world's lifestyles have changed dramatically through time as a result of technological advancements. Communication technology has advanced swiftly in the contemporary age, making a significant contribution to human existence. Smartphones are one of the most useful technologies. Mobile apps arose as a result of the evolution of regular phones into smartphones. Mobile applications with various functions give varying levels of aid to human existence. This study aims to give self-medicating patients a guideline and correct content information of over-the-counter (OTC) drugs. Subsequently, it is to develop a mobile application for the medication (E-MEDIC app). Furthermore, it is to ease and save users' time searching for medicines content. The third objective is to evaluate the user's acceptance of the medication mobile application (E-MEDIC app). The qualitative methodologies utilised for the E-MEDIC mobile app included locating two specialists to conduct an Alpha Test to obtain their thoughts and selecting twelve respondents with relevant experience to serve as testers. The experiment includes several areas of the application's functioning, usability, and interface design. All respondents and experts agreed that the E-MEDIC mobile app's functionality, usefulness, and usability are excellent. The E-MEDIC smartphone app, which is based on this initiative, can provide accurate information and content specifics on over-the-counter (OTC) medications to self-medicating patients. If properly implemented in pharmacies, OTC medications, and public health, the E-MEDIC smartphone app offers several benefits. The results from this study are promising.