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Muhammad Mahyiddin Ramli
Preferred name
Muhammad Mahyiddin Ramli
Official Name
Muhammad Mahyiddin, Ramli
Alternative Name
Ramli, Muhammad Mahyiddin
Ramli, M. Muhammad
Ramli, M. M.
Ramli, M.
Ramli, Muhammad Mahyidin
Mahyiddin Ramli, Mohd
Ramli, Muhammad M.
Main Affiliation
Scopus Author ID
55891565000
Researcher ID
AAH-1285-2021
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PublicationEvaluation of GO and rGO on breast cancer cell line (MCF7) and normal breast cell line (MCF10a) for cell viability and electrical response(Universiti Malaysia Perlis (UniMAP), 2018-12)
;Siti S. Mat Isa ;N. S. Mazlan ;L. F. A. Talip ;Rafeezul MohamedGraphene based materials become a phenomenal in various applications including biomedical devices due to their excellent properties. Their effects towards certain diseases were broadly studies and presented. However, the work has been performed was only limited to the graphene oxide (GO) and its biocompatibility only. In this work, the interaction of GO and reduced graphene oxide (rGO) on breast cancer cell (MCF7) and normal breast cell (MCF10a) was investigated specifically on the cell viability, cell mortality and current-voltage (IV) relationship. Graphene oxide and rGO at the concentration of 100μg/mL were prepared by chemical methods. The morphology and quality of both materials were characterized using AFM and Raman Spectroscopy. The cells were treated for 24 hours and the effects of these materials on the viability and mortality of the cell were observed. The interaction between graphene-based materials and both cells significantly impact the current-voltage (IV) characteristics. The results show that GO and rGO did not affect the cell viability but only small percentage different was obtained on cell mortality. It also observed that the resistance of cell treated with rGO decreased with time for MCF7 and vice versa for MCF10a. While for GO, the resistance of cell increased with time for MCF7 and vice versa for MCF10a. These clear patterns of these interactions lead to a good input for biosensor fabrication which was aimed to be used as the early diagnosis cancer stem cell point of care (POC) device. -
PublicationRemazol orange dye sensitized solar cell using graphene oxide and reduced graphene oxide working electrode(Universiti Malaysia Perlis (UniMAP), 2018-12)
;Siti S. Mat isaN. RosliDye Sensitized Solar Cell (DSSC) is said as a potential solar device which offers easy, cheaper and greener materials and preparation process. However, the efficiency of this device is still an ultimate problem and challenge. In this paper, an organic Remazol orange dye was used as the DSSC dye sensitizer which prepared with different working electrodes. The different working electrodes consist of Titanium Dioxide (TiO2) with Graphene Oxide (GO) and TiO2 with reduced Graphene Oxide (rGO). In order to analyze the adsorption characteristics of GO and rGO, the solution was tested using Ultraviolet-Visible-Near Infrared Spectrophotometry and the surface morphology of all mixed pastes was observed under Atomic Force Microscopy and Scanning Electron Microscope. Then, the device performance was tested under illumination of solar cell simulator. From overall results, the efficiency for all tested devices was quite low from expectation. For this work, the performance of TiO2-rGO DSSC at 0.138% is 84.7% higher compared to the TiO2-GO DSSC which was 0.021%. This result was obtained when the working electrode and dye less exposed to the light during dye preparation process at 24 hours soaking time.