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Normahira Mamat @ Mohamad Nor
Preferred name
Normahira Mamat @ Mohamad Nor
Official Name
Normahira, Mamat @ Mohamad Nor
Alternative Name
Mamat, N.
Mamat, Normahira
Normahira, M.
Main Affiliation
Scopus Author ID
55986880900
Researcher ID
DEH-4271-2022
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1 - 2 of 2
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PublicationBiodegradation of PLA-Pennisetum purpureum based biocomposite scaffold( 2017-10-29)
;Revati R. ; ; ; ;The in vitro degradation and mechanical properties of a 3D porous Pennisetum purpureum (PP)/polylactic acid (PLA) - based scaffold was investigated. In this study, composite scaffolds with PP to PLA ratio of 0%, 10%, 20%, and 30% were immersed in PBS solution at 37 °C for 40 days. Interestingly, the degradation rate was reduced for the PLA/PP20 scaffold, though insignificantly, this could be attributed to the improved mechanical properties and stronger fibre-matrix interface. The FESEM results indicated that a sound fibre-matrix interface was formed in the PLA/PP20 scaffold, which reflected the addition of P. purpureum into PLA decreasing the degradation rate compared to in pure PLA scaffolds. The results suggest that the P. purpureum/PLA scaffold degradation rate can be altered and controlled to meet the requirement imposed by a given tissue engineering application.1 41 -
PublicationIn vitro biodegradation, cytotoxicity, and biocompatibility of polylactic acid/napier cellulose nanofiber scaffold composites( 2022-12-31)
;Revati R. ; ; ; ;Alshahrani H.A.This study aimed to evaluate the bioactivities and biocompatibilities of porous polylactic acid (PLA) reinforced with cellulose nanofiber (CNF) scaffolds. The in vitro degradation behaviors of the porous PLA/CNF scaffolds were systematically measured for up to 8 weeks in a phosphate-buffered saline medium at 37 °C. The reinforcement of CNF resisted the biodegradation of the scaffolds. The in vitro cytotoxicity and biocompatibility of the scaffolds were determined using the Beas2B American Type Culture Collection cells. The 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide cytotoxicity and proliferation tests showed that the scaffolds were non-toxic, and epithelial cells grew well on the scaffold after 7 days of culture, whereas the percentage of cell proliferation on the PLA/CNF15 scaffold was the largest, 130 %. A scratch wound-healing assay was performed to evaluate the suitability of the scaffolds for cell migration. The results demonstrated that the scaffolds exhibited good cell migration towards nearly complete wound closure.32 2