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  1. Home
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  5. Biodegradation of PLA-Pennisetum purpureum based biocomposite scaffold
 
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Biodegradation of PLA-Pennisetum purpureum based biocomposite scaffold

Journal
Journal of Physics: Conference Series
ISSN
17426588
Date Issued
2017-10-29
Author(s)
Revati R.
Universiti Malaysia Perlis
Mohd Shukry Abdul Majid
Universiti Malaysia Perlis
Mohd Ridzuan Mohd Jamir
Universiti Malaysia Perlis
Normahira Mamat @ Mohamad Nor
Universiti Malaysia Perlis
Nashrul Fazli Mohd Nasir
Universiti Malaysia Perlis
Cheng Ee Meng
Universiti Malaysia Perlis
DOI
10.1088/1742-6596/908/1/012029
Abstract
The in vitro degradation and mechanical properties of a 3D porous Pennisetum purpureum (PP)/polylactic acid (PLA) - based scaffold was investigated. In this study, composite scaffolds with PP to PLA ratio of 0%, 10%, 20%, and 30% were immersed in PBS solution at 37 °C for 40 days. Interestingly, the degradation rate was reduced for the PLA/PP20 scaffold, though insignificantly, this could be attributed to the improved mechanical properties and stronger fibre-matrix interface. The FESEM results indicated that a sound fibre-matrix interface was formed in the PLA/PP20 scaffold, which reflected the addition of P. purpureum into PLA decreasing the degradation rate compared to in pure PLA scaffolds. The results suggest that the P. purpureum/PLA scaffold degradation rate can be altered and controlled to meet the requirement imposed by a given tissue engineering application.
Funding(s)
Ministry of Higher Education, Malaysia
File(s)
Research repository notification.pdf (4.4 MB)
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