This paper reviews several studies of image de-noising on digital image processing and applications. Noisy images contain different noise that exist either due to environment or electronic interferences. Ergo, de-noising is crucial to eliminate the noise that disturb data collecting process. The impact of de-noising on image processing can result for accurate and precise data collected from the image. Additionally, de-noising process required several crucial steps that help to enhance knowledge on digital image and its application. Hence, study and understanding de-noising can improve multiple aspect such as image quality, data sensitivity and specificity, accuracy of the collected data, and increase the percentage of each parameter.