Nanogap nanowires have gained attention for their potential applications in biosensing due to their unique physical properties, such as high surface-to-volume ratios and enhanced sensitivity. These nanowires can be used as electrodes in electrochemical biosensors, improving the sensitivity and selectivity of these devices. They can also be integrated into sensor platforms using mature nano-fabrication procedures. These advancements offer great potential for developing highly sensitive and accurate biosensors for various applications, including biomedical diagnostics, environmental monitoring, and food safety. Nanogap nanowires have revolutionized the field by providing enhanced sensitivity and accuracy in detecting biological molecules. They have also been used in the fabrication of segmented nanowires for chemical sensing, allowing for more precise and targeted detection of specific analytes. Nanogap nanowires have shown promise in protein biomarker analysis, enabling ultra-sensitive detection of protein biomarkers at low levels. This review provides an overview of recent advancements in Nanogap Nanowires and their applications in biosensing.
