In this work, polysulfone (PSf)/ hydroxyapatite (HAp) ultrafiltration mixed matrix membranes (MMMs) were prepared for wastewater treatment by using phase inversion method. The effect of hydroxyapatite (HAp) dispersion on the PSf/PVP membrane surface were investigated. Characterizations were done to observe the distribution of HAp on the membrane surface by using X-ray diffractometer (XRD) and scanning electron microscope (SEM). The XRD analysis showed the crystallinity of the HAp derived from cow bone. The dispersion of HAp in polymer matrix is a promising materials that can change the structure of the PSf membrane.