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Effect of amino acid concentration on the gold nanoparticle for Calcium Phosphate formation UV-Vis and SEM studies

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dc.contributor.author Annisa Tsalsabila
dc.contributor.author Yuliati Herbani
dc.contributor.author Yessie Widya Sari
dc.date.accessioned 2024-07-11T09:46:15Z
dc.date.available 2024-07-11T09:46:15Z
dc.date.issued 2022-12
dc.description.abstract The strong binding of amine to gold nanoparticles increases the usage of amino acids to functionalize gold nanoparticles. In this study, different charged amino acids were used as a capping agent for the gold nanoparticle to induce calcium phosphate formation. Glutamic and aspartic acid were negatively charged, while lysine and arginine were used as positively charged amino acids. The final ratio of gold to amino acid concentration (𝑐𝐴𝑢⁄𝑐𝐴𝐴) was 0.6 and 0.45. The variation concentration effect of amino acids in binding with gold nanoparticles was characterized using ultraviolet-visible (UV-Vis) spectroscopy. Slightly shifted in UV-Vis absorbance was recorded after gold nanoparticles were functionalized by amino acids indicating the existence of amino acids on gold nanoparticle surfaces. After being capped with amino acids, the solution of gold nanoparticles was tested using zeta potential, which showed the high stability of the solutions containing aspartic acid. Finally, the amino acid-capped gold nanoparticles solution was added by calcium and phosphate sources to form calcium phosphate. Interestingly, not all samples showed the existence of calcium phosphate formation based on scanning electron microscopy-energy-dispersive Xray spectroscopy (SEM-EDS) results. However, the EDS results indicate that calcium phosphate was formed on the sample that contained lysine with 0.45. The results suggest that the calcium phosphate formation on amino acid-capped gold nanoparticles depends on the amino acid and the ratio concentration of gold nanoparticles to amino acids.
dc.identifier.govdoc https://ijneam.unimap.edu.my/
dc.identifier.uri https://ijneam.unimap.edu.my/index.php/vol-15-december-2022-special-issue-bond21
dc.identifier.uri https://ijneam.unimap.edu.my/
dc.identifier.uri https://hdl.handle.net/20.500.14170/3207
dc.language.iso en
dc.relation.ispartof International Journal of Nanoelectronics and Materials (IJNeaM)
dc.relation.issn 1985-5761
dc.subject Amino acids
dc.subject Calcium phosphate
dc.subject Gold nanoparticles
dc.title Effect of amino acid concentration on the gold nanoparticle for Calcium Phosphate formation UV-Vis and SEM studies
dc.type Resource Types::text::journal::journal article
dspace.entity.type Publication
oaire.citation.endPage 202
oaire.citation.issue Special Issue BOND 21
oaire.citation.startPage 193
oaire.citation.volume 15
oairecerif.author.affiliation IPB University, Indonesia
oairecerif.author.affiliation IPB University, Indonesia
oairecerif.author.affiliation IPB University, Indonesia
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