Nurul Izni Rusli
Thumbnail Image
Preferred name
Nurul Izni Rusli
Official Name
Nurul Izni, Rusli
Alternative Name
Rusli, Nurul Izni
Rusli, N. I.
Main Affiliation
Scopus Author ID
24725647900
Researcher ID
AAU-9676-2021

Research Output

Filters

5
Reset filters

Settings
Now showing 1 - 5 of 5
Thumbnail Image
Publication

Miniaturized Electrochemical Device for In-Situ Monitoring of Glucose, Lactate, Dissolved Oxygen, PH, and Temperature in Yeast Culture

2021-06-20 , Nurul Izni Rusli , Espinar P.L. , Ceyssens F. , Taurino I. , Kraft M.

This paper presents the integration on a single chip of multiple electrochemical sensors based on amperometric and potentiometric techniques, as well as of a physical sensor. The prototype comprises six sensors for in-situ monitoring of important parameters of a bioprocess; glucose, lactate, pH, cell density, dissolved oxygen, and temperature. All sensor elements have been calibrated and showed acceptable detection performance. We also demonstrate a preliminary experiment for in-situ monitoring in a yeast culture to better understand the response of the proposed microsensors towards yeast fermentations application.

View
Thumbnail Image
Publication

A Fully-Bioresorbable Nanostructured Molybdenum Oxide-Based Electrode for Continuous Multi-Analyte Electrochemical Sensing

2024-01-01 , Fernandes C. , Franceschini F. , Smets J. , Deschaume O. , Nurul Izni Rusli , Bartic C. , Ameloot R. , Baert K. , Ustarroz J. , Taurino I.

Bioresorbable electrochemical sensors remain mostly unexplored despite their ability to provide continuous in situ measurements of critical biomarkers. The primary challenge arises from the direct exposure of the electrodes’ thin metal films to biofluids, which poses difficulties in ensuring both proper operational lifetimes and sensing performance. Molybdenum (Mo) presents itself as a promising biometal due to its uniquely gradual dissolution in biofluids, facilitated by the formation of a slower-dissolving MoOx surface layer. Consequently, carefully engineered MoOx films can endow transient electrochemical sensors with unparalleled stability during extended operational lifetimes. Herein an unprecedented sensor architecture achieved via the unique pairing of sputtered Mo and MoOx thin films, probed as a pH and dissolved oxygen sensor is reported. Compared to a bare Mo electrode, a bilayer Mo+MoOx electrode subjected to post-deposition annealing (400 °C, 60 min, N2 environment) displayed a largely improved stability (>24 h) in solution and demonstrated predictable functionality during ongoing film dissolution at 37 °C. Collectively, this work establishes a pioneering strategy for the fabrication of reliable and clinically relevant implantable electrochemical sensors.

View
Thumbnail Image
Publication

Multi-Sensor Chip for Monitoring Key Parameters in Bioprocesses

2021-09-15 , Nurul Izni Rusli , Vincentini I.P. , Ceyssens F. , Kraft M.

This paper presents a feasibility study on the integration of multiple biosensors based on amperometric, potentiometric, and impedimetric detection techniques, as well as physical sensors on a single chip. The sensor chip comprises six sensors for in-situ monitoring of important process parameters in a bioprocess: glucose, lactate, pH, cell density, dissolved oxygen concentration, and temperature. The wafer-level parallel fabrication process of multiple microsensors on a single substrate involves four relatively simple processes. The fabricated enzyme sensors were tested with a linear working range up to a concentration of 10 mM for the glucose and lactate sensors and show a fast response time of 20 s. The integrated pH sensor was governed by a near-Nernstian equation with a sensitivity of 60.8 ± 2.4 mV/pH. Cell density, dissolved oxygen, and temperature sensor were also electrically tested. Results obtained from experimental measurements can be considered a promising step towards the realization of a real-time and parallel in-situ measurement platform for bioprocesses.

View
Thumbnail Image
Publication

Output voltage control of dual input single ended primary inductor converter (SEPIC) for hybrid photovoltaic-piezoelectric system

2017-07-01 , Yong H.Y. , Nurul Izni Rusli , Mohammad Faridun Naim Tajuddin

Renewable sources are developing fast and widely used to reduce the non-renewable sources. In this paper, a standalone, portable, green energy dependent, dual input SEPIC converter is developed with a 12 V DC output voltage The control strategy for this converter is designed to retain output voltage within 12 V when inputs source is in the wide range of 6V to 24V. Sharing only the output capacitor method is one of the multi-input method and has been used to combine two input energy which are solar and vibration in this research. This system contains feedback system and is designed by using Proportional Integral Derivative (PID) controller to ensure the output voltage is 12V. The converter with the controller has no overshoot, it settling time is about 0.02 second and the rise time is about 0.0001 second. Thus, it is proved the converter with controller is capable to reduce the settling time and rise time compare to converter without controller.

View
No Thumbnail Available
Publication

On-chip nanostructured electrochemical cells for enhanced glucose monitoring in bioprocesses

2022-01-01 , Nurul Izni Rusli , Van Den Eeckhoudt R. , Ceyssens F. , Taurino I. , Kraft M.

In this work, we exploit template-free electrodeposition based on chronocoulometry to deposit a homogeneous nanostructured Pt film on a miniaturized Pt electrode. The results demonstrate that the introduction of a nanostructured surface remarkably improves the performance of miniaturized Pt electrode as a glucose sensor. The nanostructured Pt electrode produces larger current response than that of the bare Pt electrode with an identical apparent area. It also had a higher current response and a wider linear range owing to the presence of larger surface area.

View