Nurul Izni Rusli
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Preferred name
Nurul Izni Rusli
Official Name
Nurul Izni, Rusli
Alternative Name
Rusli, Nurul Izni
Rusli, N. I.
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Scopus Author ID
24725647900
Researcher ID
AAU-9676-2021

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  • Publication
    Miniaturized Electrochemical Device for In-Situ Monitoring of Glucose, Lactate, Dissolved Oxygen, PH, and Temperature in Yeast Culture
    ( 2021-06-20)
    Nurul Izni Rusli
    ;
    Espinar P.L.
    ;
    Ceyssens F.
    ;
    Taurino I.
    ;
    Kraft M.
    This paper presents the integration on a single chip of multiple electrochemical sensors based on amperometric and potentiometric techniques, as well as of a physical sensor. The prototype comprises six sensors for in-situ monitoring of important parameters of a bioprocess; glucose, lactate, pH, cell density, dissolved oxygen, and temperature. All sensor elements have been calibrated and showed acceptable detection performance. We also demonstrate a preliminary experiment for in-situ monitoring in a yeast culture to better understand the response of the proposed microsensors towards yeast fermentations application.
      1
  • Publication
    On-chip nanostructured electrochemical cells for enhanced glucose monitoring in bioprocesses
    (IEEE Computer Society, 2022-01-01)
    Nurul Izni Rusli
    ;
    Van Den Eeckhoudt R.
    ;
    Ceyssens F.
    ;
    Taurino I.
    ;
    Kraft M.
    In this work, we exploit template-free electrodeposition based on chronocoulometry to deposit a homogeneous nanostructured Pt film on a miniaturized Pt electrode. The results demonstrate that the introduction of a nanostructured surface remarkably improves the performance of miniaturized Pt electrode as a glucose sensor. The nanostructured Pt electrode produces larger current response than that of the bare Pt electrode with an identical apparent area. It also had a higher current response and a wider linear range owing to the presence of larger surface area.
      2  3
  • Publication
    A Fully-Bioresorbable Nanostructured Molybdenum Oxide-Based Electrode for Continuous Multi-Analyte Electrochemical Sensing
    ( 2024-01-01)
    Fernandes C.
    ;
    Franceschini F.
    ;
    Smets J.
    ;
    Deschaume O.
    ;
    Nurul Izni Rusli
    ;
    Bartic C.
    ;
    Ameloot R.
    ;
    Baert K.
    ;
    Ustarroz J.
    ;
    Taurino I.
    Bioresorbable electrochemical sensors remain mostly unexplored despite their ability to provide continuous in situ measurements of critical biomarkers. The primary challenge arises from the direct exposure of the electrodes’ thin metal films to biofluids, which poses difficulties in ensuring both proper operational lifetimes and sensing performance. Molybdenum (Mo) presents itself as a promising biometal due to its uniquely gradual dissolution in biofluids, facilitated by the formation of a slower-dissolving MoOx surface layer. Consequently, carefully engineered MoOx films can endow transient electrochemical sensors with unparalleled stability during extended operational lifetimes. Herein an unprecedented sensor architecture achieved via the unique pairing of sputtered Mo and MoOx thin films, probed as a pH and dissolved oxygen sensor is reported. Compared to a bare Mo electrode, a bilayer Mo+MoOx electrode subjected to post-deposition annealing (400 °C, 60 min, N2 environment) displayed a largely improved stability (>24 h) in solution and demonstrated predictable functionality during ongoing film dissolution at 37 °C. Collectively, this work establishes a pioneering strategy for the fabrication of reliable and clinically relevant implantable electrochemical sensors.
      1  21