Now showing 1 - 4 of 4
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Biodegradation of PLA-Pennisetum purpureum based biocomposite scaffold

2017-10-29 , Revati R. , Mohd Shukry Abdul Majid , Mohd Ridzuan Mohd Jamir , Normahira Mamat @ Mohamad Nor , Nashrul Fazli Mohd Nasir , Cheng Ee Meng

The in vitro degradation and mechanical properties of a 3D porous Pennisetum purpureum (PP)/polylactic acid (PLA) - based scaffold was investigated. In this study, composite scaffolds with PP to PLA ratio of 0%, 10%, 20%, and 30% were immersed in PBS solution at 37 °C for 40 days. Interestingly, the degradation rate was reduced for the PLA/PP20 scaffold, though insignificantly, this could be attributed to the improved mechanical properties and stronger fibre-matrix interface. The FESEM results indicated that a sound fibre-matrix interface was formed in the PLA/PP20 scaffold, which reflected the addition of P. purpureum into PLA decreasing the degradation rate compared to in pure PLA scaffolds. The results suggest that the P. purpureum/PLA scaffold degradation rate can be altered and controlled to meet the requirement imposed by a given tissue engineering application.

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Influence of cellulose filler extracted from napier grass on thermal characterizations, moisture content, tensile strength, biodegradation, and morphological structure of bioplastic films

2022-01-01 , Tuan Rohadi T.N. , Mohd Ridzuan Mohd Jamir , Mohd Shukry Abdul Majid , Normahira Mamat @ Mohamad Nor , Sulaiman M.H.

This paper reports on the effects of Napier grass (NG) cellulose used as a filler on the thermal characterizations, moisture content, tensile strength, biodegradation, and morphological structure of bioplastic films. Bioplastic films were obtained from chitosan and gelatin; and from the fiber, bark, and whole of Napier grass (NG). The films were prepared by solution casting with 1, 1.5, 2, and 2.5 wt.% of cellulose content. Alkali and bleaching treatments were performed on the cellulose using 8% sodium hydroxide and 1.7% sodium chlorite. The results reveal that the tensile strength of the bioplastic film with 2 wt.% of fiber filler was the highest and decreased when the cellulose filler loading was 2.5 wt.%. Increasing the cellulose loading accelerated the biodegradation rate of the bioplastic films. The addition of the fiber filler had improved compatibility among the components and the barrier properties of the film that led to a less-porous film.

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Cure Behaviour and Tensile Properties of Pineapple Leaf Fibre Reinforced Natural Rubber Composites

2024-03-01 , Xuan, Yeo Yi , Mohd Ridzuan Mohd Jamir , Mohd Shukry Abdul Majid , Mohd Shihabudin Ismail , Yudhanto F. , Normahira Mamat @ Mohamad Nor , Fauziah Che Mat

Short natural fibres replace synthetic fibres as filler in natural rubber (NR) as they are environmentally beneficial and sustainable. This study investigates the cure behaviour and tensile properties of pineapple leaf fibre (PALF) reinforced NR composites at various fibre contents. The fibre contents are varied at 0, 10, 20 and 30 parts per hundred rubber (phr). PALF reinforced NR composites are prepared using a two-roll mill. Surface morphology of tensile fractured specimens is examined using scanning electron microscopy (SEM). The results demonstrated that the optimum cure time decreases significantly with greater fibre content. The hardness value increases gradually with increasing filler content. The stress-strain graphs show an increasing trend in stress at higher fibre content particularly at low strain regions. On the contrary, the tensile strength reduces when the fibre content is increased up to 30 phr. SEM analysis reveals that the fibre-matrix adhesion is considerably poor due to the fibre pullout phenomenon observed. It is indicated that higher fibre content could be possibly reinforced to NR to achieve high deformation stress at incredibly low strain regions.

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In vitro biodegradation, cytotoxicity, and biocompatibility of polylactic acid/napier cellulose nanofiber scaffold composites

2022-12-31 , Revati R. , Mohd Shukry Abdul Majid , Mohd Ridzuan Mohd Jamir , Normahira Mamat @ Mohamad Nor , Cheng Ee Meng , Alshahrani H.A.

This study aimed to evaluate the bioactivities and biocompatibilities of porous polylactic acid (PLA) reinforced with cellulose nanofiber (CNF) scaffolds. The in vitro degradation behaviors of the porous PLA/CNF scaffolds were systematically measured for up to 8 weeks in a phosphate-buffered saline medium at 37 °C. The reinforcement of CNF resisted the biodegradation of the scaffolds. The in vitro cytotoxicity and biocompatibility of the scaffolds were determined using the Beas2B American Type Culture Collection cells. The 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide cytotoxicity and proliferation tests showed that the scaffolds were non-toxic, and epithelial cells grew well on the scaffold after 7 days of culture, whereas the percentage of cell proliferation on the PLA/CNF15 scaffold was the largest, 130 %. A scratch wound-healing assay was performed to evaluate the suitability of the scaffolds for cell migration. The results demonstrated that the scaffolds exhibited good cell migration towards nearly complete wound closure.