Most of people are unaware that some of the indicators of optic pathway diseases such as stroke or tumor can be detected from the loss part of human vision, or referred as visual field defect. Ophthalmologist will manually examine the site, size and margin of the lesion from patient’s visual field points mapped by Humphrey Field Analyzer. Different site, size and margin of lesion indicates different type of defects and disease that associated with it. Therefore, an effective automated detection mechanism of multi class visual field defect is in demand to help decision making by ophthalmologist. In this paper, we review multiple techniques of supervised and unsupervised learning method for detection of optic pathway disease.