The paper aimed to determine the validity of finite element analysis of tibia bone affected by Osteogenesis Imperfecta (OI) under various angle of bowing of the bone. Finite element (FE) model of human tibia bones were developed with various degree of bowing to simulate different severity of OI, and then the geometrical models of these FE models were used to develop bone specimen using fused deposition method (FDM) rapid prototyping technique. Compression tests were conducted to the bone specimen and FE analysis were performed by simulating conditions of the compression test, and then results from the compression test and FE simulation were compared. It have been found that both of the results corresponded to each other, therefore it is concluded that FE analysis is able to simulate the mechanical response of tibia bone with OI.
