Publication:
Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads

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cris.author.scopus-author-id 57212345291
cris.author.scopus-author-id 57215715847
cris.author.scopus-author-id 54683507500
cris.author.scopus-author-id 22137274300
cris.author.scopus-author-id 12776687500
cris.author.scopus-author-id 56650753300
dc.contributor.author Tan L.C.
dc.contributor.author Som M.H.M.
dc.contributor.author Basaruddin K.S.
dc.contributor.author Yazid H.
dc.contributor.author Sulaiman A.R.
dc.contributor.author Awang M.S.
dc.date.accessioned 2024-12-14T04:21:29Z
dc.date.available 2024-12-14T04:21:29Z
dc.date.issued 2019-08-01
dc.description.abstract Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy fractures. The femur consists of cortical and cancellous bone, each with different mechanical properties. Bone fractures often occur throughout patients' lifetime. However, doctors still have no quantitative method to predict fractures. Therefore, this project's purpose is to investigate the OI femoral fracture risk to help prevent fractures. The project consists of three sections; cortical and cancellous segmentation, reconstruction of 3D OI femoral model and finite element analysis (FEA) of the OI femur to obtain fracture risk. The fracture risk in daily activities and the fracture load were examined. All the stress values were judged by the fracture criteria, assumed as 115 MPa. The exercises that exerted force more than 6 times of body weight can cause fractures. In addition, the optimal compressive force and tensile force were 919.7 N and 912.1 N, respectively, while medial and lateral impact were 230.8 N. Cancellous bone was not affected even a fracture happen. Based on these findings, we can conclude that when the OI femur is subjected to lateral or medial forces, the femur breaks easily. The bone can be reconstructed into a solid body without having to separate bone into cortical and cancellous.
dc.identifier.scopus 2-s2.0-85081755251
dc.identifier.uri https://hdl.handle.net/20.500.14170/10767
dc.relation.funding Ministry of Higher Education, Malaysia
dc.relation.grantno FRGS/1/2016/TK03/UNIMAP/02/6
dc.relation.ispartof International Journal of Mechanical and Mechatronics Engineering
dc.relation.ispartofseries International Journal of Mechanical and Mechatronics Engineering
dc.relation.issn 22272771
dc.subject Femur | Finite element analysis | Fracture risk | Osteogenesis imperfecta (OI)
dc.title Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
dc.type Journal
dspace.entity.type Publication
oaire.citation.endPage 108
oaire.citation.issue 4
oaire.citation.startPage 100
oaire.citation.volume 19
oairecerif.affiliation.orgunit Universiti Malaysia Perlis
oairecerif.affiliation.orgunit Universiti Malaysia Perlis
oairecerif.affiliation.orgunit Universiti Malaysia Perlis
oairecerif.affiliation.orgunit Universiti Malaysia Perlis
oairecerif.affiliation.orgunit Universiti Sains Malaysia, Health Campus
oairecerif.affiliation.orgunit International Islamic University Malaysia
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person.identifier.orcid #PLACEHOLDER_PARENT_METADATA_VALUE#
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person.identifier.scopus-author-id 57212345291
person.identifier.scopus-author-id 57215715847
person.identifier.scopus-author-id 54683507500
person.identifier.scopus-author-id 22137274300
person.identifier.scopus-author-id 12776687500
person.identifier.scopus-author-id 56650753300
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