The mechanic of diaphyseal fracture in human cortical femur bone depends on the bone fracture resistance. At microscale, composition and nanomechanical properties of diaphysis femur at all cortices may contributes to the fragility of fracture. This paper present a finite homogeneity model of two-dimensional micromechanical diaphysis cortical femur bone subjected to Mode I loading condition. The fracture parameter e.g. stress intensity factor (SIF) and strain energy release rate are evaluated based on linear elastic fracture mechanics (LEFM) theory. The finite element (FE) modeling were simulated for four anatomical positions in cortical bone which are posterior, anterior, medial and lateral at different variability of bone properties, associated to transverse crack which is isotropy linked to its microstructure. The results indicate a good agreement to the analytical formulation for brittle fracture. However, by using displacement extrapolation method, all cortices resulted with same value of SIF but not for strain energy release rate.
