This study delves into the causes of the symptoms of bipolar disorder among teachers and examined how it was related to meeting standards of work performance. Participants were 81 male and 119 female secondary school teachers in North Malaysia. Participants were given the surveys based on three independent variables which are stress, mood and emotions and work environment that were empirically evident to become the source of bipolar disorder symptoms. Results suggested that all of the independent variables are correlated with work performance; with the highest result being for work environment (.48**), then mood and emotions (.47**) and finally stress (.38**). Results are discussed in terms of implications for teachers to excel in their work performance.