Zulkarnay Zakaria
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Preferred name
Zulkarnay Zakaria
Official Name
Zulkarnay, Zakaria
Alternative Name
Zakaria, Z. N.
Zakaria, Zulkarnay
Zakaria, Z.
Main Affiliation
Scopus Author ID
24403085300
Researcher ID
F-5218-2010

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An Overview of Medical Applications in Meningitis Detection

2020-07-09 , Abdulrahman Ahmed A. , Zulkarnay Zakaria , Hamood Ali M. , Pusppanathan J. , Zarina Mohd Mhji S. , Anas Mohd Noor , Mohd Hafiz Fazalul Rahiman , Muhamad Khairul Ali Hassan , Muhammad Juhairi Aziz Safar , Ahmad Faizal Salleh

Meningitis remains one of the common infections among young children with high morbidity and mortality rates. In Southeast Asian, only few studies were reported published which evaluated meningitis clinically in the last two decades. Similarly, few studies in Malaysia evaluated meningitis among adolescents and children. Globally, more than one million cases with 135,000 deaths has been recorded yearly, and in Malaysia, severe neurological complications occurs in 9-25% of cases which affirms the most serious risk manifests from bacterial meningitis. Therefore, early detection and effective treatment are required before the irreversible damages occur. This paper reviews the current states and perspectives of diagnostic techniques on meningitis detection. Currently, there are three diagnostic techniques available for meningitis detection, such as blood cultures, spinal tap (lumbar puncture), and imaging techniques (CT scan, MRI, EIT, Ultrasonography, Nuclear imaging and X-ray). However, these techniques have limitations that may limit the chances of carrying out the early detection of the disease. The essence of this review is that meningitis requires an effective technique that is capable of carrying out the early detection of the disease by differentiating normal people and Meningitis infected patients so as to promote longevity worldwide. In this review magnetic induction tomography (MIT) technique is proposed to diagnose meningitis earlier as it is non-intrusive, non-invasive, contactless, and electrode-less imaging technique which does not expose the patients to a harmful radiation.

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A Review on Magnetic Induction Spectroscopy potential for fetal acidosis examination

2022-02-01 , Siti Fatimah Abdul Halim , Zulkarnay Zakaria , Pusppanathan J. , Anas Mohd Noor , Ahmad Nasrul Norali , Mohd Hafiz Fazalul Rahiman , Muji S.Z.M. , Rahim R.A. , Engku-Husna E.I. , Muhamad Khairul Ali Hassan , Muhammad Juhairi Aziz Safar , Ahmad Faizal Salleh , Mohd Hanafi Mat Som

Fetal acidosis is one of the main concerns during labor. Currently, fetal blood sampling (FBS) has become the most accurate measurement of acidosis detection. However, it is invasive and does not provide a real time measurement due to laboratory procedures. Delays in diagnosis of acidosis have caused serious injury to the fetus, especially for the brain and the heart. This paper reviews the new technique in diagnosis of acidosis non-invasively. Magnetic Induction Spectroscopy (MIS) has been proposed to be a new device for acidosis detection in recent years. This paper explains the basic principle of MIS and outlines the design specifications and design considerations for a MIS pH probe. It is expected that readers will gain a basic understanding of the development of a MIS pH probe from this review.

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Single Channel Magnetic Induction Measurement for Meningitis Detection

2021-01-01 , Aiman Abdulrahman Ahmed , Zulkarnay Zakaria , Ali M.H. , Pusppanathan J. , Rahim R.A. , Muji S.Z.M. , Anas Mohd Noor , Mohd Hafiz Fazalul Rahiman , Muhamad Khairul Ali Hassan , Muhammad Juhairi Aziz Safar , Ahmad Faizal Salleh

Bacterial meningitis is one of the most common and prominent infections which infects the central nervous system through the tissue layers and membranes that cover our brain and spinal cord. It is a staggering and fatal illness that kills patients within hours. The number of meningitis cases that has been recorded annually around the world are one million cases and 135,000 deaths. Early detection and start of sufficient treatment are considered as the main determinants for better result. MIT mechanism is noncontact electrodes of impedance measurement. This mechanism uses induction principle instead of contact electrodes to get the required information. This paper presents an overview on the potential of Magnetic induction tomography (MIT) in detecting meningitis disease. In MIT principle, single channel measurement process which consist of transmitter (Tx) and receiver (Rx) coil has been studied. In this field is disclosed about passive electrical field (PEP) which focuses on the three parameters which are dielectric permittivity, electrical conductivity, and magnetic permeability. In addition, this research project involves experimental setup. The applied frequency is between 1–10 MHz. Finally, in this project, the performance of the square coil with 12 number of turns (5Tx–12Rx) with 10 MHz frequency has been identified as the suitable transmitter-receiver pair and the optimum frequency for detecting the conductivity property distribution of brain tissues.

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