Now showing 1 - 10 of 17
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Preliminary studies on antimicrobial activity of extracts from aloe vera leaf, citrus hystrix leaf, zingiber officinale and Sabah snake grass against bacillus subtilis

2018 , Muhammad Nur Aiman Uda , Subash Chandra Bose Gopinath , Nur Hulwani Ibrahim , Mohd Khairul Rabani Hashim , Nuradibah Mohd Amer , Midhat Nabil Ahmad Salimi , Tan Ewe Shen , Ong Yee Fen , Maisara Azad Mat Akhir , Uda Hashim

Herbal plants have several potential antimicrobial activities either as antifungal or antibacterial to fight against the disease and pathogen that attack the plants. The extractions of the Aloe vera leaf, Citrus hystrix leaf, Zingiber officinale rhizome and Sabah snake grass were selected in this study to fight against Bacillus subtilis. B. subtilis is a Gram-positive bacterium, rodshaped and catalase-positive that lives on decayed organic material. It is known as Gram-positive bacteria because of its thick peptidoglycan and would appear purple when subjected to Gram test. This species is commonly found in the upper layers of the soil, in meat or vegetables, in pastry, cooked meat, in bread or poultry products. The extracts of Sabah Snake Grass found to be most effective than A.vera leaf, Z. officinale, and C. hystrix against the B. subtilis.

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Influence of carbonization conditions and temperature variations on the characteristics of coconut shell carbon

2024-03 , Yee Wen Yap , Nurul Najiha Abu Bakar , Norsuria Mahmed , Midhat Nabil Ahmad Salimi , Siti Norsaffirah Zailan , Azlin Fazlina Osman , Kamrosni Abdul Razak , Shayfull Zamree Abd. Rahim , Mohd Yusry Mohamad Yunus

This research aims to study the impact of carbonization atmospheres (ambient and nitrogen) and temperature on the properties of the coconut shell carbon (CSC) formed. To characterize the properties of CSC, the char yield percentage was calculated. Scanning Electron Microscopy (SEM) was used to study the surface morphology of CSC while X-ray Diffraction (XRD) analysis was done to identify the degree of graphitization. The carbon formed by carbonization under the nitrogen atmosphere yields lower char percentages compared to the ambient atmosphere. When the carbonization temperature elevated, both atmospheres produced a lower char yield percentage. This result is aligned with the SEM analysis where more and larger pores were observed from the carbon produced at higher temperatures and the result was further enhanced under a nitrogen atmosphere. It was found that the char yield of CSC decreased from 20.9% to 11.4% when the carbonization temperature increased from 400°C to 1000°C under the ambient atmosphere. More significant changes were formed through the carbonization process under the nitrogen atmosphere (from 18.3% to 6.03%). Pores formed when the volatile materials are released due to the elevated carbonization temperature, resulting in a reduction in total weight thus, the char yield percentage. From the XRD, all CSC produced from both atmospheres with varying temperatures poses an amorphous XRD pattern. However, the right shifted peak and the presence of an additional peak of ~40° suggest that under different temperatures and atmospheres, the crystallinity of the CSC produced was affected. This research provides insight for optimizing CSC production in the future to enhance the application of CSC.

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Production of Iron Oxide nanoparticles by co-precipitation method with optimization studies of processing temperature, pH and stirring rate

2020 , Beh Hui Hui , Midhat Nabil Ahmad Salimi

Iron Oxide Nanoparticle, maghemite (γ-Fe2O3) has received great interest and extensively used in biomedical field. Optimization studies were carried out in the production of γ-Fe2O3 nanoparticles by using co-precipitation method. Iron (II) chloride and iron (III) chloride were used as precursors which are dissolved in distilled water followed by centrifugation, drying and grinding process in order to obtain dried dark brown precipitated γ-Fe2O3 powder. The effect of different processing temperature (30 to 70°C), pH (10 to 12) and stirring rate (300 to 700rpm) towards crystallite size of γ-Fe2O3 were investigated by using Response Surface Methodology (RSM) and Central Composite Design (CCD). Based on analysis of variance (ANOVA), the determination coefficient, R2 obtained was 0.9890 where stirring rate was the parameter that affected the most on the crystallite size. Optimization processing condition that produce smallest crystallite size of 7.3657 nm was 50 °C, pH 11.40 and 550 rpm by using Design of Expert software (DOE). Characterization of γ-Fe2O3 powder samples were evaluated by using different analytical tools such as Fourier Transform Infrared (FTIR), X-Ray Diffractometer (XRD) and Scanning Electron Microscope (SEM). Iron oxide group (Fe-O), hydroxyl (OH-) group and carbon dioxide (CO2) were identified in FTIR spectrum. The characteristic peak occurring at 2θ = 35.4° indicated presence of γ-Fe2O3 in the samples. The γ-Fe2O3 particles appeared generally in spherical shape in SEM analysis.

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Toughening mechanism of thermoplastic starch nano-biocomposite with the hybrid of nanocellulose/nanobentonite

2023 , Lai Di Sheng , Azlin Fazlina Osman , Sinar Arzuria Adnan , Mariatti Jaafar@Mustapha , Ismail Ibrahim , Midhat Nabil Ahmad Salimi

High flexibility and toughness are key criteria for an effective bioplastic packaging film. However, in most studies, the flexibility of thermoplastic starch (TPS) films is always neglected when targeting their tensile strength improvement. Low film flexibility has limited the development of TPS films in replacing the petrochemical-based plastic packaging films. In this communication, we report a method to produce thermoplastic corn starch (TPCS) films with excellent mechanical strength, high flexibility and high toughness through the hybridization of two natural nanofillers: nanobentonite and nanocellulose. The synergistic effect of the hybrid nanofillers can be observed through the arrangement of alternating nacre structures where the nanobentonite silicate layers are responsible for mechanical strength, while the nanocellulose promotes free volume in the TPCS matrix and triggers high film elongation at break. Structural, morphological, and thermomechanical analysis were conducted, and the detailed strengthening mechanism of the TPCS hybrid nano-biocomposite films was revealed.

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Glucose production from sugarcane bagasse by two stages chemical pretreatment & hydrolysis

2020 , Nurul Syiffa Husna Che Roslan , Midhat Nabil Ahmad Salimi

The aim of this work was to produce glucose from sugarcane waste. It consists of high cellulose, hemicellulose and lignin which enables to be converted into a glucose production. Three conditions of acid hydrolysis was measured by using One Factor at a Time (OFAT) which consist of sulphuric acid concentration, retention time and temperature. The highest yield and optimum conditions from OFAT parameters were further continue with the enzymatic hydrolysis by using Central Composite Design (CCD). The optimization of enzymatic hydrolysis for the conversion of cellulose to glucose was conducted by using three independent variables which were pH, temperature and enzyme dosage. Based on the data of Design of Expert (DOE) software from optimization of enzymatic hydrolysis, the optimum glucose production was determined by using Dinitrosalicylic Acid Reagent (DNS) method.

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Green synthesized strontium oxide nanoparticles by Elodea canadensis extract and their antibacterial activity

2022-06-01 , Anbu P. , Subash Chandra Bose Gopinath , Midhat Nabil Ahmad Salimi , Letchumanan I. , Subramaniam S.

The production of strontium oxide nanoparticles from an aquatic plant extract is described here. UV–vis spectroscopy at ~ 220 nm was used to confirm the biosynthesis of these particles, and the color of the mixtures altered from colorless to green. The morphology of Elodea canadensis strontium oxide nanoparticles (EcSrONPs) was characterized using FE-SEM. FE-SEM images demonstrated that these particles adopted disordered, irregular shapes with agglomeration and slightly smooth surfaces. FE-TEM confirmed the results of FE-SEM analysis. These particles were also evaluated using XRD, XPS, and FTIR. The XRD pattern revealed a face-centered cubic crystalline structure at (209) and (217), while the XPS results verified the presence of both strontium and oxygen in the synthesized EcSrONPs. FTIR results confirmed that phytochemical functional groups served as capping agents during EcSrONP synthesis. In addition, zeta potential analysis confirmed the stability of EcSrONPs. Finally, the antibacterial potential of the produced EcSrONPs against Escherichia coli and Bacillus subtilis was evaluated. The largest inhibitory zone against E. coli (diameter, 22 mm) and B. subtilis (diameter, 20 mm) was observed at a EcSrONPs concentration of 24 Âµg·mL−1. Collectively, the findings of this research show that the biosynthesis of EcSrONPs is a viable option for developing novel materials for biomedical applications.

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Synthesis and characterization of reduced graphene oxide using the aqueous extract of Eclipta prostrata

2020-08-01 , Chuah Regnant , Subash Chandra Bose Gopinath , Anbu P. , Midhat Nabil Ahmad Salimi , Ahmad Radi Wan Yaakub , Lakshmipriya Thangavel

In this study, biological deoxygenation of graphene oxide (GO) using an Eclipta prostrata phytoextract was performed via the infusion method. The presence of oxide groups on the surface of graphene and removal of oxides groups by reduction were characterized through morphological and structural analyses. Field emission scanning electron microscopy images revealed that the synthesized GO and rGO were smooth and morphologically sound. Transmission electron microscopy images showed rGO developing lattice fringes with smooth edges and transparent sheets. Atomic force microscopy images showed an increase in the surface roughness of graphite oxide (14.29 nm) compared with that of graphite (1.784 nm) due to the presence of oxide groups after oxidation, and the restoration of surface roughness to 2.051 nm upon reduction. Energy dispersive X-ray analysis indicated a difference in the carbon/oxygen ratio between GO (1.90) and rGO (2.70). Fourier-transform infrared spectroscopy spectrum revealed peak stretches at 1029, 1388, 1578, and 1630 cm−1 for GO, and a decrease in the peak intensity after reduction that confirmed the removal of oxide groups. X-ray photoelectron microscopy also showed a decrease in the intensity of oxygen peak after reduction. In addition, thermogravimetric analysis suggested that rGO was less thermally stable than graphite, graphite oxide, and GO, with rGO decomposing after heating at temperatures ranging from room temperature to 600 Â°C.

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Experimental study on laser welding dissimilar materials

2021-07-21 , Noorhafiza Muhammad , Yap How Hean , Mohd Shuhidan Saleh , Midhat Nabil Ahmad Salimi , Mohd Fathullah Ghazli@Ghazali , Muhamad Farizuan Rosli

Laser welding on dissimilar materials is widely used and has significance application in industry. Laser welding is the one of the method which can offer high strength of joint especially for joining of dissimilar metals contrast to conventional method. Conventional welding more often had an insufficient penetration depth and a wider heat affected zone which prompts to reduce joint quality. This work exhibits a weld possibility on low carbon steel and high carbon steel surface utilizing low power fiber laser in pulse wave modes. The objective of this research work is to investigate the influence of laser welding parameters of welding speed and pulse width on weld geometry of the welded metal. The parameters used is the welding speed (1.67 mm/s to 8.33mm/s) and pulse width (3 ms to 5 ms). The optimum weld geometry was with the largest aspect ratio (1.42) with parameter of welding speed (1.67 mm/s) and pulse width (3.0 ms). As conclusion, appropriate utilization of parameters can improve the quality of weld joints and durability of products.

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A review on additive manufacturing in bioresorbable stent manufacture

2021-07-21 , Noorhafiza Muhammad , Azli A.A. , Mohd Shuhidan Saleh , Midhat Nabil Ahmad Salimi , Mohd Fathullah Ghazli@Ghazali , Shayfull Zamree Abd. Rahim

Vascular injury and disease as well as cardiac and cardiovascular diseases have been a serious threat to human life and health today. Stents implantation have been the primary treatment for vascular diseases. Polymeric bioresorbable stents manufactured with 3D printer is newly emerged. This work review the bioresorbable stents and the utilization of additive manufacturing in bioresorbable stent manufacture.

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Malaria Parasite Diagnosis Using Computational Techniques: A Comprehensive Review

2021-12-01 , Wan Azani Wan Mustafa , Hiam Alquran , Muhammad Zaid Aihsan , Mohd Saifizi Saidon , Wan Khairunizam Wan Ahmad , Aimi Salihah Abdul Nasir , Mohamed Mydin Hj M.Abdul Kader , Midhat Nabil Ahmad Salimi , Mohd Wafi Nasrudin

Malaria is a very serious disease that caused by the transmitted of parasites through the bites of infected Anopheles mosquito. Malaria death cases can be reduced and prevented through early diagnosis and prompt treatment. A fast and easy-to-use method, with high performance is required to differentiate malaria from non-malarial fevers. Manual examination of blood smears is currently the gold standard, but it is time-consuming, labour-intensive, requires skilled microscopists and the sensitivity of the method depends heavily on the skills of the microscopist. Currently, microscopy-based diagnosis remains the most widely used approach for malaria diagnosis. The development of automated malaria detection techniques is still a field of interest. Automated detection is faster and high accuracy compared to the traditional technique using microscopy. This paper presents an exhaustive review of these studies and suggests a direction for future developments of the malaria detection techniques. This paper analysis of three popular computational approaches which is k-mean clustering, neural network, and morphological approach was presented. Based on overall performance, many research proposed based on the morphological approach in order to detect malaria.