Nur Farahiyah Mohammad
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Nur Farahiyah Mohammad
Official Name
Nur Farahiyah, Mohammad
Alternative Name
Mohammad, N. F.
Nur Farahiyah, Mohammad
Mohammad, N.
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Scopus Author ID
36872346600
Researcher ID
X-6539-2019

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The total phenolic content, total flavonoid content and antioxidant properties of E.tirucalli L. extract partitioned using different solvents

2025 , Mangalagowri Sangar , Nur Farahiyah Mohammad , Siti Shuhadah Md Saleh , Alwani Ibrahim , Farah Diana Mohd Daud , Roy Francis Navea , Khairul Farihan Kasim , Nashrul Fazli Mohd Nasir

E.tirucalli L. is a succulent plant native to Africa renowned for its medicinal properties and antioxidant activity. This study aimed to evaluate the total phenolic and flavonoid content as well as the antioxidant activity of E.tirucalli L. extracts obtained using different solvents. Aqueous ethanol, hexane, and dichloromethane were used for extraction through Soxhlet extraction and partitioning. The total phenolic content was highest in the aqueous ethanol extract (2.501 mg GAE/g), followed by hexane (0.110 mg GAE/g) and dichloromethane (0.050 mg GAE/g) extracts. Similarly, the total flavonoid content was highest in the aqueous ethanol extract (1.307 mg QE/g), followed by hexane (0.164 mg QE/g) and dichloromethane (0.061 mg QE/g) extracts. The DPPH assay demonstrated that the aqueous ethanol extract exhibited the highest radical scavenging activity (RSA) with an IC50 value of 36.89 ± 0.05 μg/mL, followed by dichloromethane (50.94 ± 0.39 μg/mL) and hexane (62.42 ± 1.34 μg/mL) extracts. These findings indicate that aqueous ethanol is an effective solvent for extracting phenolic and flavonoid compounds with potent antioxidant activity from E.tirucalli L. extracts.

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Effect of Nitrate Acid Treated Dolomite on the Tensile Properties of Ultra-High Molecular Weight Polyethylene (UHMWPE) Composites

2024-01-01 , Abdullah S.F.A. , Saleh S.S.M. , Nur Farahiyah Mohammad , Syarifah Nuraqmar Syed Mahamud , Mohd Firdaus Omar , Akil H.M.D. , Chang B.P. , Saliu H.R. , Rostam N.H. , Gondro J.

Ultra-High Molecular Weight Polyethylene (UHMWPE) polymers have been used in biomedical applications due to its biocompatibility, durability, toughness and high wear resistance. To enhance the mechanical properties, various types of minerals are commonly utilized as fillers in UHMWPE. One of the minerals is dolomite, which has been recognized as a valuable mineral with versatile applications, particularly in the field of biomedical applications. This paper presents the tensile properties of UHMWPE composites that filled with dolomite and treated-dolomite at various filler loading (i.e., 1-5 wt.%). Nitric acid and diammonium phosphate were used to treat the dolomite. From the results, the peaks of the FTIR spectrum displays carbonate (CO3–2), phosphate (PO4–3) and hydroxyl (OH–) groups in the ct-dolomite powder sample while the XRD pattern reveals that using dolomite treated with 1M nitric acid resulted in the presence of calcium hydroxide phosphate (Ca10(PO4)5(OH)) and MgO. For tensile strength, UHMWPE/ct-dolomite composites show better tensile strength than the pure UHMWPE composites. Treated improve the dolomite filler and resulted in significantly better matrix-filler interfacial interactions and improve the properties.

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Preliminary study of the polymesoda expansa based hydroxyapatite for medical devices coating application

2020-12-15 , Roslan M.R. , Nashrul Fazli Mohd Nasir , Khalid M.F.A. , Gilani M.A. , Nur Farahiyah Mohammad , Cheng Ee Meng , Zoolfakar A.S. , Nasrul Amri Mohd Amin , Shah Fenner Khan Mohamad Khan

Hydroxyapatite (HA) which is a group of calcium phosphate (CaP) is used as a medical devices coating due to its ability to increase the bioactivity and biocompatibility of the device surface. The attraction of using waste seashells products is interesting due to its sustainability and low cost solution especially in biomedical application. Polymesoda expansa or locally known as Lokan is potentially rich with calcium carbonate (CaCO3). Here, the synthesis of HA was done via precipitation method by utilizing the Polymesoda expansa (Lokan) shells as the resource of calcium precursors. Hydroxyapatite synthesized from Polymesoda expansa was carried out with different pH solution (pH 9 and 13) in alkaline environment. The effects of pH on the morphological and chemical composition properties as well as the Ca/P ratio of HA powders were analyzed through Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), and Energy Dispersive X-ray Spectrometry (EDS). The finding demonstrates as the pH increases, the calcium apatite reduced and this had increases the Ca/P ratio.

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Characterization of silica powder prepared from acid leaching and thermal treatment of RHA

2024 , Mudrikah Sofia Mahmud , Farah Diana Mohd Daud , Norshahida Sarifuddin , Hafizah Hanim Mohd Zaki , Norhuda Hidayah Nordin , Nur Farahiyah Mohammad

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Synthesizing and Optimization the Hydroxyapatite Based on Corbiculacea Seashells

2021-01-01 , Mohd Riza Mohd Roslan , Nashrul Fazli Mohd Nasir , Nur Farahiyah Mohammad , Cheng Ee Meng , Nasrul Amri Mohd Amin , Abdul Khalid M.F. , Mohd Zakimi Zakaria , Muhammad Mokhzaini Azizan , Muzammil Jusoh

Hydroxyapatite (HA) is one of the main components in bone which functions to enhance its cell regeneration. Synthetically produced HA, based on seashell resources has higher biocompatibility, and in high demand especially in bone tissue engineering. However, the secondary phase of HA production are calcium oxide and carbonate, which impedes its performance. HA is synthesized via wet chemical precipitation and optimization were done to obtain nearly pure HA by manipulating the pH value and sintering temperature. It is expected that the combination of these parameters will optimize the amount of secondary phase hence attained nearly stoichiometric or pure HA. HA powders were analyzed through Fourier Transform Infrared Spectroscopy (FTIR) and Energy Dispersive X-ray Spectrometry (EDX).

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Quantification of polyphenols content and antioxidant activity of Euphorbia Tirucalli l. extracted using Maceration and Soxhlet method

2025 , Alwani Ibrahim , Nur Farahiyah Mohammad , Siti Shuhadah Md Saleh , Nashrul Fazli Mohd Nasir , Khairul Farihan Kasim , Mangalagowri Sangar , Farah Diana Mohd Daud , Roy Francis Navea

Euphorbia tirucalli L. (E. tirucalli) has gained attention for these past few years in terms of its phytochemical studies due to the antioxidant attribution of polyphenols source as its bioactive compounds in extracts. In order to extract important plant compounds, conventional extraction methods such as maceration and Soxhlet are still widely incorporated for plant extraction techniques due to their convenient application in laboratory settings. This study focused on the two conventional techniques; maceration and Soxhlet on polyphenols extraction of E. tirucalli using various extraction solvents. In order to provide insight into its potential for polyphenols extraction, yield percentage (%) and phytochemical tests such as Total Phenolic Content (TPC), Total Flavonoid Content (TFC), and antioxidant activity (%) were assessed. In terms of yield percentage, Soxhlet methanolic extract was found to be the best. The findings also suggest that both maceration and Soxhlet techniques are effective in extracting a significant amount of phenolics and flavonoid content in which highest value recorded were 17.26 ± 0.23 mgGAE/100g and 50.08 ± 1.13 mgQE/100g for maceration while 16.17 ± 0.21 mgGAE/100g and 43.02 ± 0.01 mgQE/100g for Soxhlet. Maceration with methanol solvent appears to be more effective for TPC and TFC while Soxhlet acetonic extract is chosen as the best for antioxidant activity with 75 .79 ± 0.04 % of radical scavenging activity in E. tirucalli extract. Thus, this study indicates the noteworthy potential of both maceration and Soxhlet techniques for polyphenols extraction.

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Malaysian seashells based Hydroxyapatite for biomedical application

2023 , Nur Farahiyah Mohammad , Mohd Riza Mohd Roslan , Nashrul Fazli Mohd Nasir

Hydroxyapatite (HA, Ca10 (PO 4 ) 6 (OH) 2 ) is widely used in dentistry and orthopaedics as a bone substitute or replacement material. The material is chemically and crystallographically identical to the mineral component of human biological bone. Natural materials such as animal bones, clay, eggshells, corals, and seashells can be used as a main source of calcium precursor to synthesise HA. Using Malaysian shell waste materials is sustainable and economical. Thus, these advantages have attract researchers to explore potential products from shell trash. This chapter presents the synthesis method and characterisation of hydroxyapatite synthesised from several Malaysian local seashells such as Paphia textile (lala), Corbiculacea (etok), and Polymesoda expansa (lokan) shells.

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Nano Hydroxyapatite (Nano-HA) based on pholas orientalis shells and degradation analysis

2023-04 , Mohd Riza Mohd Roslan , Nashrul Fazli Mohd Nasir , Nur Farahiyah Mohammad , Farah Diana Mohd Daud , Cheng Ee Meng , Beh Chong You

Millions of tons of seashells are produced every day as waste around the world. These underutilized seashells waste was executed as calcium precursor by researcher to synthesis the nano-hydroxyapatite (nano-HA). Nano-HA was successfully synthesised from Pholas Orientalis seashells waste via the chemical precipitation method. Different sintering temperatures were implemented to evaluate the physicochemical criteria of nano-HA. The obtained powders were examined by various physicochemical methods such as XRD, FTIR, FESEM, EDX and degradation analysis. The peaks in XRD and FTIR analysis the HA is successfully produced. The FESEM images on the other hand showing the HA particle in nano size range with rice-like structure. Meanwhile, a variation of Ca/P ratio can be observed in respect to sintering temperatures. The Ca/P ratio for HA-WS, HA-S500 and HA-S700 sample is 1.78, 2.03 and 1.57 respectively. Different sintering temperatures result in different crystallinity value which consequently affects its degradation profile.

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Effect of surfactant concentrations on pore characteristics of mesoporous carbonated Hydroxyapatite prepared by soft-templating hydrothermal method

2018-11 , Nur Farahiyah Mohammad , R. Othman , A. A. Abdullah , F. Y. Yeoh

Mesoporous carbonated hydroxyapatite is a promised material for the application in drug delivery. Mesoporous carbonated hydroxyapatite (CHA) was synthesised through a hydrothermal co-precipitation method using different concentration (1.7, 7, 10 and 14 mM) of non-ionic surfactant P123 as a pores template. The crystalline phase, chemical composition, morphology and pore size distribution of mesoporous CHA were analysed using various materials characterisation techniques. The presence of mesopores as an array of pore channels in the synthesised sample were confirmed using transmission electron microscope. The optimum pore characteristics (i.e. surface area = 78 m2g-1, pore size = 27 nm and pore volume = 0.542 nm) of mesoporous CHA was obtained when surfactant concentration (1.7 mM) was maintained closed to critical micelle concentration (CMC), 0.0044 mM.

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Properties of carbon nanotubes-calcium carbonate hybrid filled epoxy composites

2020-01-01 , Siti Shuhadah Md Saleh , Suhaimi S.M. , Md Akil H. , Nur Farahiyah Mohammad

Carbon nanotubes (CNTs) have a great potential to be used as filler to enhance the mechanical properties of polymer composites due to excellent properties. However, CNTs have limitation of difficult to disperse in polymer matrix. The hybridization of CNTs and inorganic fillers can improve the dispersion and combine their properties in polymer composites. In the present work, the properties of the epoxy composites filled with carbon nanotube-calcium carbonate (CNTs-CaCO3) hybrid, at various filler loading (i.e., 1-5 wt.%) were studied. The CNTs-CaCO3 hybrid fillers were prepared by physically mixing (PHY) method and chemical vapor deposition (CVD) method. The tensile properties and hardness of both composites were investigated at different weight percentages of filler loading. The CNTs-CaCO3 CVD hybrid composites showed higher tensile strength and hardness than the CNTs-CaCO3 PHY hybrid composites. This increase was associated with the homogenous dispersion of CNT–CaCO3 particle filler. The morphological studies of fracture surfaces after tensile test by means of SEM showed homogenous dispersion of CNTs-calcium carbonate CVD hybrid in epoxy matrix. The result shows that the CNTs-calcium carbonate CVD hybrid composites are capable in increasing tensile strength by up to 116.4%, giving a tensile modulus of 40.3%, and hardness value of 39.2% as compared to a pure epoxy.

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