Norhidayah Abd Aziz
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Preferred name
Norhidayah Abd Aziz
Official Name
Norhidayah, Abd Aziz
Alternative Name
Abd Aziz, Norhidayah
Main Affiliation
Scopus Author ID
57215817360
Researcher ID
EJY-4327-2022

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Medical healthcare M2M system using the VLC system

2020-01-08 , Norhidayah Abd Aziz , Anuar Mat Safar , Mohd Rashidi Che Beson , Syed Alwee Aljunid Syed Junid , Rosdisham Endut

The RF communication has suffered from the interference and excessive latency issues. It is required a separated setup for transmission and reception of RF waves. To overcome this problem, the VLC system is a chosen technique due to high bandwidth and immunity to interference from electromagnetic sources. In this project, Optisystem Software version 15 has been chosen to study the perfomances of the VLC system in directed LOS. The performance results will be displayed on BER analyser and the simulation that has been done is iterating continuously in order to get the acceptable results. The result indicates that the reading of simulation of 1 user for both bit rate 155Mbps and 622Mbps shows the best result compared to 4 users. Without using any kind of OCDMA system, the number of users will reach the limitations which is not more than 4 users. The number of users influences the performance of the system and the result shows the decrement of BER reading which is lower than 10-9.

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Evaluation of various lignocellulosic biomass and cereal grains as potential spawn materials for wild Schizophyllum commune cultivation

2020-12-18 , Siti Aminah Mohd Hassan , Sam Sung Ting , Nur Zatul 'Iffah Zakaria , Norhidayah Abd Aziz , Zarina Zakaria , Nurfatirah N. , Azhar M.

Rapid mycelium growth in spawn production and on growth substrate could suppress contamination, which is significant in mushroom industry. The aim of the study is to investigate the potential of lignocellulosic biomass waste as new materials alternative to common cereal grains in producing spawn for wild S. commune cultivation on rice husk, paddy straw, and rubber wood sawdust. The fastest mycelium growth among lignocellulosic biomass was found on rice husk spawn (1.27 cm/day) and 1.98 cm/day for wheat grain. The shortest duration for substrate colonization for both lignocellulosic and grain spawn is on paddy straw, followed by rice husk, and rubber wood sawdust.

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Growth Optimisation of Bacillus subtilis in medium supplemented with prebiotic gum Arabic

2020-12-18 , Norhidayah Abd Aziz , Noor Hasyierah Mohd Salleh , Abu Hassan A.F. , Amira Farzana Samat , Adilah Anuar , Siti Aminah Mohd Hassan , Lian Ou Li

Bacillus subtilis is a type of gastrointestinal bacteria that build up a healthy gut microbiota. The bacterial species has been well documented to involve in maintaining a healthy gut homeostasis in which disruption in it's microbial composition or "dysbiosis"has recently been linked to obesity. Probiotic in vivo restoration of dysbiosed microbiota have been proved successful in obese CD-1 mice model. However, prebiotic study using Gum Arabic (GA) assessing to optimise an in vitro lumen system specifically targeting to enhance the growth of B. subtilis are still lacking since this bacteria are depleted in obese individuals. Thus, this study aimed to establish the optimal growth conditions in simulated in vitro lumen system and to the best of our knowledge, this is the first in vitro study attempted to optimize the growth of B. subtilis in medium supplemented with prebiotic GA. Growth screening analysis suggested an optimal dosage of 1.0% and 0.5% glucose and GA, respectively. The highest growth rate was recorded at 0.7995 hours-1 with doubling time of 52.02 minutes with extended period of stationary phase. The optimal GA concentration and fermentation conditions were determined at 0.67%, pH 7.4 and temperature of 37 C. The validated suggested model indicates that the supplementation of GA into an optimal fermentation systems is promising to enhance the growth of gut microflora Bacillus subtilis, for restoration of a dysbiosed gut microbiota in vitro.

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Corticomotor excitability after two different repetitive transcranial magnetic stimulation protocols in haemorrhagic stroke patients

2020 , Asrarul Fikri Hassan , Muhammad Hafiz Hanafi , Zamzuri Idris , Jafri Malin Abdullah , Saiful Azli Nayan , Norhidayah Abd Aziz

Intracerebral haemorrhage (ICH) or haemorrhagic stroke can be managed medically or by surgical evacuation of the hematoma. However, several authors have reported no significant difference when compared between both interventions in haemorrhagic stroke patients. We aimed to assess the use of Transcranial Magnetic Simulation (TMS) as supportive of medical and surgical interventions to assist the rehabilitation process in haemorrhagic stroke patient. A randomized control trial was performed on twenty nine patients and randomized into three groups; (1)Facilitatory, (2)Inhibitory and (3)Sham group. Patient underwent two weeks of TMS Stimulation protocol for total of 10 sessions. The pre and post Motor Evoked Potential (MEP) reading between groups were compared and analyzed. Our result indicated that regardless of patient's age and ICH clot size, the improvement in MEP score after TMS facilitatory protocol was significantly higher compared to the Sham protocol group (p = 0.02). Such correlation however, was not observed in the inhibitory protocol group (p = 0.175). Collectively, our finding had demonstrates TMS potential as a safe and non-invasive tool for supportive management of ICH stroke as patients and that patient with stable ICH will have better motor function recovery post rTMS facilitatory protocol regardless of their age and clot size.

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Protein extraction of Momordica Charantia seed assisted by ultrasound extraction

2023 , Muhamad Ikmal Sirozi , Noor Hasyierah Mohd Salleh , Mohd Amin Zainal Abidin , Norhidayah Abd Aziz , Siti Aminah Mohd Hassan , Zarina Zakaria

The Momordica charantia is a tropical and subtropical plant with high nutritional value that has been implemented in traditional folk medicine as an antifungal, antimutagenic, Anthelmintic, anticancer, antifertility, and antidiabetic agent. The seeds contain rich source of antifungal protein that can be explored to be used against various fungus disease. In this study, the antifungal protein was extracted by using ultrasound assisted extraction (UAE) via one-factor-at-a-time (OFAT) technique with following the parameter sodium chloride, NaCl concentration (0.5, 1.0, 1.5, 2.0 and 2.5 M), solute ratio (0.1, 0.2, 0.3, 0.4 and 0.5 g/mL) and extraction time (4, 6, 8, 10 and 12 min). After extraction, the extract was further centrifuged and assayed by standard Bradford method before analysing the protein content at 595 nm. The result shows the optimum conditions for protein content is 6.445 mg/mL achieved after treatment with 1.5 M NaCl, 1w;10v (g/mL) in 10 min with p-value < 0.01 from each of parameter. Results showed that Momordica charantia seed had desired protein source with optimal parameter and promising antifungal bioresources with prospective applications in food and other industries.

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Enzymatic assisted Citronella essential oil extraction from Cymbopogan Winterianus

2015 , Norhidayah Abd Aziz

The essential oil of Citronella is commonly extracted via typical steam distillation of citronella plan parts. However, the oil yield is generally low (0.22% - 1.0%), causing burden to many entrepreneurs to meet the strong demand. Therefore, the study was conducted to improve the yield of citronella oil recovery by introducing an optimised enzymatic assisted pre-treatment using crude microbial enzymes isolated from the soil surrounding the citronella roots. Firstly, the lignocellulosic components of dried citronella roots were investigated to evaluate the most abundance component for selection of enzymes useful for pre-treatment. The composition analysis has identified cellulose as the major lignocellulosic component (38.21%±1.65), followed by hemicellulose (30.49%±0.93), lignin (21.12%±1.86) and extractives (4.97%±0.22). 31 out of 52 isolated strains have been identified as positive cellulase producer. Based on the calculated cellulolytic indexes, 4 strains i.e; UniMAPF7, UniMAPF16, UniMAPF24, and UniMAPF27 were selected for application in the laboratory scale pre-treatment process. Results from the growth curve analysis and enzyme activity study suggested that the optimal time for enzyme harvesting occurred at day 5 for UniMAPF7, day 4 for UniMAPF24 and day 3 for UniMAPF16 and UniMAPF27. Laboratory scale oil extraction of pre-treated citronella root with crude enzymes of UniMAPF7 and UniMAPF24 yielded in a significant 2.5-fold and 1.7-fold increased in citronella oil recovery, respectively, when compared to the untreated citronella root as control.

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Evaluation of various lignocellulosic biomass and cereal grains as potential spawn materials for wild Schizophyllum commune cultivation

2020 , Siti Aminah Mohd Hassan , Sam Teek Ling , N Z I Zakaria , Norhidayah Abd Aziz , Zarina Zakaria , N Nurfatirah , M Azhar

Rapid mycelium growth in spawn production and on growth substrate could suppress contamination, which is significant in mushroom industry. The aim of the study is to investigate the potential of lignocellulosic biomass waste as new materials alternative to common cereal grains in producing spawn for wild S. commune cultivation on rice husk, paddy straw, and rubber wood sawdust. The fastest mycelium growth among lignocellulosic biomass was found on rice husk spawn (1.27 cm/day) and 1.98 cm/day for wheat grain. The shortest duration for substrate colonization for both lignocellulosic and grain spawn is on paddy straw, followed by rice husk, and rubber wood sawdust.

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Optimization of an ultrasound-assisted extraction method for phenolic content in Momordica Charantia seeds and its antifungal activity against Pleurotus Ostreatus Green Mold Pathogen

2023-09 , Norhidayah Abd Aziz , Noor Hasyierah Mohd Salleh , Nur Umi Masjida Ahmad Fauzi , Azlina Harun Kamaruddin , Muhamad Ikmal Sirozi , Zarina Zakaria , Subash Chandra Bose Gopinath , Amira Farzana Samat

Phenolic compounds from fruits and plant parts showed several biological properties such as antifungal activity. This study reports the optimized conditions for total phenolic content (TPC) extraction from Momordica charantia seeds using ultrasound-assisted extraction and its antifungal activity against Pleurotus pulmonarius green mold (GM) pathogens. Using water as solvent, a response surface methodology (RSM) was employed involving three independent factors including liquid to solid ratio (LSR) (10:1–60:1), pH (3.0–9.0), and extraction time (2–8 min). ANOVA suggested only parameters of pH and LSR were significant to produce TPC yield of 166.7 mg GAE/g, at optimized conditions of pH9.0 and LSR 10:1. The antifungal activity of optimized momordica seed extract (MSE) was tested against P. pulmonarius GM pathogens; Trichoderma sp., Aspergillus flavus and Penicillium citrinum. MSE presented antifungal activities against all tested strains, in a dose and strain-dependent manner. The highest growth inhibition was achieved when using 2.5 ml of extract for both Trichoderma sp. and P. citrinum with 63.1% and 89.2% inhibition, respectively. Meanwhile, 3.5 ml of extract was needed to achieve 79% inhibition on A. flavus. Conclusively, the use of non-toxic green solvent such as water, assisted with ultrasound power, is useful to produce MSE with antifungal activities as an alternative approach to chemical fungicides for the protection of grey oyster mushroom from GM pathogen.

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The Effect of Chemical Treated Spent Mushroom Substrate (SMS) on Lignocellulosic Content

2023-01-01 , Adi M.R.M. , Tengku Nuraiti Tengku Izhar , Norlia Mohamad Ibrahim , Norhidayah Abd Aziz , Hadiyanto H. , Matei M.

A by-product of the mushroom industry, spent mushroom substrate (SMS) is primarily made of lignocellulosic agricultural waste. SMS contains cellulose (38-46.6%), lignin (25-34.5%), and hemicellulose (19-27.7%) and is nutrient-rich. The primary objectives of this study included the characterization of SMS, analysis of lignocellulosic content prior to and following pre-treatment, analysis of the effects of various NaOH concentrations with varying molarities (1.0 to 5.0 Molar), and analysis of surface morphology using a scanning electron microscope (SEM). The result that comparison between untreated and treated sample The result for untreated are contain high amount of lignin from 23.85% to 27.39% and for treated are amount reduce from 20.6% to 23.85%. The difference of NaOH concentration from 1.0 to 5.0 Molar, so the best pre-treatment is alkaline pre-treatment from 1.0 to 3.0 M are the best concentration to treat SMS sample from alkaline pre-treatment and proved sodium hydroxide pre-treatment as an effective method to reduce the hemicellulose and lignin contents. Images clearly showed how the pre-treatment could alter the biomass's structural makeup and distort it, increasing the surface area that was open to enzymatic attack. The pre-treated SMS's surface had numerous sporadic pores and cracks. The study's findings demonstrated that SMS from the P. sajor-caju species has the potential to provide a new source of glucose for bioethanol production.

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Botanical insecticide of chili and ginger extract on Nilaparvata lugens, brown planthopper

2020 , Noor Hasyierah Mohd Salleh , Norhidayah Abd Aziz , Alina Rahayu Mohamed , Adilah Anuar , I Nur Humaira

Invasion of Nilaparvata lugens or brown planthopper (BPH) in paddy fields has led to the use of excessive chemical insecticides due to its effectiveness. However, excessive applications has contributed several negative effects on the environment, farmers as well as non-targeting organisms. As an alternative, a mixture of a botanical insecticide containing mixture of chili and ginger extracts have been studied. Three parameters were studied namely the extract concentration, time of exposure and temperature of exposure. The results showed that 90% of BPH mortality was found at 40% extract concentration with 72 hr duration time of exposure at optimal temperature 30 C. HPLC analysis proved the presence of capsaicin and gingerol at peaks of 4.502 min and 11.046 min respectively. From repellency analysis, the BPH showed selective repel action against the treated paddy. This is due to the pungent odor contributed from compound of gingerol, shogaol and capsaicin presented in the mixture. Meanwhile, contact toxicity studies have successfully give 100% of mortality of BPH. Microscopic analysis have shown BPH deformities was increased by the extract concentration.

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