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Profiling secondary metabolites from lichen “Parmotrema perlatum (Huds.) M.Choisy” and antibacterial and antioxidant potentials

cris.author.scopus-author-id 57991159300
cris.author.scopus-author-id 58610593900
cris.author.scopus-author-id 57990882900
cris.author.scopus-author-id 43861575400
cris.author.scopus-author-id 7006558013
cris.author.scopus-author-id 57219716693
cris.virtual.department Universiti Malaysia Perlis
cris.virtualsource.department 3f983c2e-28f9-4f7e-9c19-b081a6c20fd8
dc.contributor.author Dwarakanath P.R.
dc.contributor.author Abinaya K.
dc.contributor.author Nagasathya K.
dc.contributor.author Meenakumari S.
dc.contributor.author Subash Chandra Bose Gopinath
dc.contributor.author Raman P.
dc.date.accessioned 2024-10-04T00:56:10Z
dc.date.available 2024-10-04T00:56:10Z
dc.date.issued 2022-01-01
dc.description.abstract Parmotrema perlatum lichen is traditionally used as a spice in Indian households and also to treat diseases such as eczema, respiratory diseases, pulmonary diseases, and arthritis. This study emphasizes the extraction of secondary metabolites from foliose lichen P. perlatum with antioxidant and antibacterial activity. The secondary metabolites extracted from P. perlatum using hexane, chloroform, and methanol were analysed by gas chromatography-mass spectrometry (GC–MS) and liquid chromatography-mass spectrometry (LC–MS/MS) shows that P. perlatum extracts possess 2,4-dihydroxy-3,6-dimethyl-methyl ester, 1,4-benzenediol, atraric acid, orcinol, benzoic acid, 2,5-dimethyl- resorcylic acid, and savinin, tetrahydroterotri-L- glutamate, primidolol, ustiloxin, mallotinic acid, and mecambrine. The efficacy of three solvent extracts of lichen against Gram-negative bacteria Pseudomonas aeruginosa, Chromobacterium violaceum, and Gram-positive Lactobacillus plantarum was tested. The methanol extract of P. perlatum has the highest antibacterial activity against the tested bacteria at a concentration of 10 µg/ml as compared with the other two solvent extracts. The antioxidant potential of P. perlatum was determined using ferric ion reducing antioxidant power, 2,2-diphenyl-1-picrylhydrazyl, 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), and nitric oxide scavenging activity assays, which exhibit that all extracts showed radical scavenging potential. Graphical Abstract: [Figure not available: see fulltext.]
dc.identifier.doi 10.1007/s13399-022-03572-0
dc.identifier.scopus https://link-springer-com.ezproxyunimap.idm.oclc.org/content/pdf/10.1007/s13399-022-03572-0.pdf?utm_source=scopus&getft_integrator=scopus
dc.identifier.uri https://link-springer-com.ezproxyunimap.idm.oclc.org/article/10.1007/s13399-022-03572-0
dc.language.iso en
dc.relation.funding Universidade de Aveiro
dc.relation.grantno 13GW0479B
dc.relation.ispartof Biomass Conversion and Biorefinery
dc.relation.ispartofseries Biomass Conversion and Biorefinery
dc.relation.issn 21906815
dc.subject Antibacterial
dc.subject Antioxidant
dc.subject GC–MS
dc.subject Kalpasi
dc.subject LC–MS
dc.subject Lichen
dc.subject Secondary metabolites
dc.title Profiling secondary metabolites from lichen “Parmotrema perlatum (Huds.) M.Choisy” and antibacterial and antioxidant potentials
dc.type Resource Types::text::journal::journal article
dspace.entity.type Publication
oaire.citation.endPage 16471
oaire.citation.issue 14
oaire.citation.startPage 16461
oaire.citation.volume 14
oairecerif.affiliation.orgunit SRM Institute of Science and Technology
oairecerif.affiliation.orgunit SRM Institute of Science and Technology
oairecerif.affiliation.orgunit SRM Institute of Science and Technology
oairecerif.affiliation.orgunit SRM Institute of Science and Technology
oairecerif.affiliation.orgunit Universiti Malaysia Perlis
oairecerif.affiliation.orgunit SRM Institute of Science and Technology
oairecerif.author.affiliation SRM Institute of Science and Technology, India
oairecerif.author.affiliation SRM Institute of Science and Technology, India
oairecerif.author.affiliation SRM Institute of Science and Technology, India
oairecerif.author.affiliation SRM Institute of Science and Technology, India
oairecerif.author.affiliation Universiti Malaysia Perlis
oairecerif.author.affiliation SRM Institute of Science and Technology, India
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person.identifier.scopus-author-id 57991159300
person.identifier.scopus-author-id 58610593900
person.identifier.scopus-author-id 57990882900
person.identifier.scopus-author-id 43861575400
person.identifier.scopus-author-id 7006558013
person.identifier.scopus-author-id 57219716693
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