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Polymer conjugated gold nanoparticles in biomedical applications

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cris.author.scopus-author-id 57191227462
cris.author.scopus-author-id 7006558013
cris.virtual.department Universiti Malaysia Perlis
cris.virtualsource.department 3f983c2e-28f9-4f7e-9c19-b081a6c20fd8
dc.contributor.author Stanley Anniebell
dc.contributor.author Subash Chandra Bose Gopinath
dc.date.accessioned 2025-01-14T02:01:17Z
dc.date.available 2025-01-14T02:01:17Z
dc.date.issued 2018-01-01
dc.description.abstract Background: Research interest on the properties of polymer conjugated gold nanoparticle (GNP) in biomedicine is rapidly rising because of the extensive evidences for their unique properties. In the field of biomedicine, GNPs have been widely used because of their inertness and low levels of cytotoxicity. Therefore, when exposed to cells, they are less prone to exert damaging effects. GNPs are capable of being functionalized as desired and are ideal as they do not encourage undesired side reactions that might counter react with the intention of the functionalization. Biofouling is an occurrence that takes place at cellular and biological molecular level, binds non-specifically on the detection surface and forms a wrong output. This undesired incidence can be avoided by conjugating the surface of biomolecules with polymers. Densely packed repeating chains of polymers such as polyethylene glycol are capable of decreasing non-specific reactions. Applications of polymer conjugated GNPs in the field of biomedicine are as biosensors, delivery and therapeutic agents. Conclusion: Therefore, the properties and applications of polymer conjugated GNPs are studied widely as overviewed here.
dc.identifier.doi 10.2174/0929867324666170116123633
dc.identifier.pmid 28093984
dc.identifier.scopus 2-s2.0-85041399540
dc.identifier.uri https://hdl.handle.net/20.500.14170/13537
dc.identifier.uri https://pubmed.ncbi.nlm.nih.gov/28093984/
dc.language.iso en
dc.publisher Bentham Science Publishers
dc.relation.grantno undefined
dc.relation.ispartof Current Medicinal Chemistry
dc.relation.issn 09298673
dc.subject Polyethylene glycol
dc.subject Biofouling
dc.subject Biomedical applications
dc.subject Biomedicine
dc.subject Gold nanoparticle
dc.subject Polymer
dc.title Polymer conjugated gold nanoparticles in biomedical applications
dc.type Journal
dspace.entity.type Publication
oaire.citation.endPage 1445
oaire.citation.issue 12
oaire.citation.startPage 1433
oaire.citation.volume 25
oairecerif.affiliation.orgunit Universiti Malaysia Perlis
oairecerif.affiliation.orgunit Universiti Malaysia Perlis
oairecerif.author.affiliation Universiti Malaysia Perlis
oairecerif.author.affiliation Universiti Malaysia Perlis
person.identifier.orcid #PLACEHOLDER_PARENT_METADATA_VALUE#
person.identifier.orcid #PLACEHOLDER_PARENT_METADATA_VALUE#
person.identifier.scopus-author-id 57191227462
person.identifier.scopus-author-id 7006558013
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