In this study rice bran protein were extracted and powdered using spray dryer. The optimization of the process were done using Box-Behkenn response surface design. Process parameter such as temperature (120°C,165°C,210°C), aspirator (52%,66%,80%) feed flow rate (5%,30%,55%) and air flow rate (20%,30%55%) were investigated. The result show that the extraction condition have significant effects on extraction yield of protein the obtained experimental data were fitted to a quadratic equation using multiple regression analysis with high coefficient of determination value of 0.8137.an optimization study using Derringer's desired function methodology was performed and the optimal conditions based on both individual and combinations of all independent variable for yield (temperature is 120˚C, Aspirator is at 80% feed flowrate set to 5% and air flowrate of 42mmhg) and protein (temperature is 120˚C, aspirator were set at 79.9%, feed flowrate set to 31.8% and air flowrate of 51mmhg) were determined with maximum protein yield of 17.29% per 50 gram of raw rice bran (RRB)
