The CNC milling machine was used to machine the specimens made from stainless steel AISI 316 based on the selected parameters setting. Specimens with 6 mm in thickness obtaining was used. The material removal rate (MRR) was calculated by dividing machine time the weight of the specimen weight before and after the cutting process. The second performance surface roughness (SR) and it was measured by MITUTOYO CS-3100 device. Taguchi Method was utilized as in layout the experimental to optimize MRR, SR. It was found that prediction maximum value MRR was 4.86 mm3/s under setting spindle speed 2500 m/min , feed rate 250 mm/min , and depth of cut 0.1 mm . On the other hand the prediction minimum SR value 2.85 μm, was under setting spindle speed 500 m/min, feed rate 250 mm/min, and depth of cut 0.2 mm. Confirmation tests were run to verify. The prediction it was found the experimental results of MRR and SR for within 10% percentage of the prediction value.