Publication:
The importance, benefits, and future of nanobiosensors for infectious diseases
The importance, benefits, and future of nanobiosensors for infectious diseases
Date
2024-04-01
Authors
Dhahi T.S.
Dafhalla A.K.Y.
Saad S.A.
Zayan D.M.I.
Ahmed A.E.T.
Elobaid M.E.
Tijjani Adam
Subash Chandra Bose Gopinath
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue
Abstract
Infectious diseases, caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi, are crucial for efficient disease management, reducing morbidity and mortality rates and controlling disease spread. Traditional laboratory-based diagnostic methods face challenges such as high costs, time consumption, and a lack of trained personnel in resource-poor settings. Diagnostic biosensors have gained momentum as a potential solution, offering advantages such as low cost, high sensitivity, ease of use, and portability. Nanobiosensors are a promising tool for detecting and diagnosing infectious diseases such as coronavirus disease, human immunodeficiency virus, and hepatitis. These sensors use nanostructured carbon nanotubes, graphene, and nanoparticles to detect specific biomarkers or pathogens. They operate through mechanisms like the lateral flow test platform, where a sample containing the biomarker or pathogen is applied to a test strip. If present, the sample binds to specific recognition probes on the strip, indicating a positive result. This binding event is visualized through a colored line. This review discusses the importance, benefits, and potential of nanobiosensors in detecting infectious diseases.
Description
Keywords
diagnosis | infectious disease | nanobiosensors | outbreak | transmission