This study investigates the dynamics of fluid flow in the cooling channels of the graphics processing unit (GPU) blocks, focusing on the effects of varying inlet and outlet diameters as well as the shape of the pipes on the maximum pressure and temperature within the system. The primary objectives are: first, to evaluate the different inlet and outlet diameters (5 mm, 10 mm, and 15 mm) that impact peak pressure and temperature; second, to examine the influence of pipe designs on these parameters. Computational Fluid Dynamics (CFD) simulations were conducted to model and analyze these variations using SimFlow 4.0. The findings reveal significant correlations between the geometric configurations and the flow characteristics, with specific diameters and designs leading to notable changes in maximum temperature. These insights provide a deeper understanding of optimizing cooling channel designs for improved thermal management in GPUs. The study concludes by emphasizing the critical role of geometric parameters in the performance of cooling systems and suggesting directions for further research.