This paper studies on the performance of semiconductor optical amplifiers and microfiber Mach-Zehnder interferometer in the loop mirror of multi-wavelength Brillouin fibre laser configuration. The microfiber Mach-Zehnder interferometer is designed by the using the Optisystem and OptiBPM software. This project has shown that the proposed configuration with semiconductor optical amplifiers and Mach-Zehnder interferometer in the loop mirror has the ability to generate multiple signals. Input BP power of 4dBm has been identified as optimum input power for this configuration since it resulted higher number of output signals generation compared to other input BP power which is from -6dBm, -5dBm to 8dBm The configuration also has the capability to generate up to 19 dominant overall number of output signals at injected SOA current of 0.8A, whereas the minimum SOA current of 0.5A is only required to initiate first signal at input BP power - 6dBm. In conclusion, this paper has successfully demonstrates that of semiconductor optical amplifiers and microfiber Mach-Zehnder interferometer in loop mirror multi-wavelength Brillouin fibre laser configuration can effectively act to generated multiple signals. This multi-wavelength Brillouin fibre laser configuration can be utilized in many applications, especially in optical sensing and for optical communication, since this two field need large scale of number of signals in order to accommodate better results.