This paper analyses the duct flow pressure and velocity using SimFlow 4.0, a Computational Fluid Dynamics (CFD) software. The primary objective of the study is to investigate the fluid behavior within duct systems, focusing on critical parameters such as pressure distribution and velocity profiles. The simulation considers two independent parameters: the inlet diameter of the duct flow and the number of the outlet duct flow. The results demonstrate that the variations in duct design and inlet conditions influence the overall performance, highlighting critical regions of pressure distribution and velocity changes. The correlations between the inlet diameter and number of outlets with the pressure and velocity are studied. This analysis provides valuable insights for optimizing ductwork in various engineering applications, ensuring efficient and effective fluid transport. Besides, the study emphasizes the importance of CFD tools like SimFlow in predicting and enhancing the performance of duct systems.