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Lumped-element circuit modeling for composite scaffold with nano-hydroxyapatite and wangi rice starch

2023 , Xiao Jian Tan , Cheng Ee Meng , Nashrul Fazli Mohd Nasir , Mohd Shukry Abdul Majid , Mohd Ridzuan Mohd Jamir , Khor Shing Fhan , Kim Yee Lee , Kok Yeow You , Che Wan Sharifah Robiah Mohamad

Mechanistic studies of the interaction of electromagnetic (EM) fields with biomaterials has motivated a growing need for accurate models to describe the EM behavior of biomaterials exposed to these fields. In this paper, biodegradable bone scaffolds were fabricated using Wangi rice starch and nano-hydroxyapatite (nHA). The effects of porosity and composition on the fabricated scaffold were discussed via electrical impedance spectroscopy analysis. The fabricated scaffold was subjected to an electromagnetic field within the X-band and Ku-band (microwave spectrum) during impedance/dielectric measurement. The impedance spectra were analyzed with lumped-element models. The impedance spectra of the scaffold can be embodied in equivalent circuit models composed of passive components of the circuit, i.e., resistors, inductors and capacitors. It represents the morphological, structural and chemical characteristics of the bone scaffold. The developed models describe the impedance characteristics of plant tissue. In this study, it was found that the ε′ and ε″ of scaffold composites exhibited up and down trends over frequencies for both X-band and Ku-band. The circuit models presented the lowest mean percentage errors of Z′ and Z″, i.e., 3.60% and 13.80%, respectively.

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Lumped-element circuit modeling for composite Scaffold with Nano-Hydroxyapatite and Wangi Rice Starch

2023 , Xiao Jian Tan , Cheng Ee Meng , Nashrul Fazli Mohd Nasir , Mohd Shukry Abdul Majid , Mohd Ridzuan Mohd Jamir , Khor Shing Fhan , Kim Yee Lee , Kok Yeow You , Che Wan Sharifah Robiah Mohamad

Mechanistic studies of the interaction of electromagnetic (EM) fields with biomaterials has motivated a growing need for accurate models to describe the EM behavior of biomaterials exposed to these fields. In this paper, biodegradable bone scaffolds were fabricated using Wangi rice starch and nano-hydroxyapatite (nHA). The effects of porosity and composition on the fabricated scaffold were discussed via electrical impedance spectroscopy analysis. The fabricated scaffold was subjected to an electromagnetic field within the X-band and Ku-band (microwave spectrum) during impedance/dielectric measurement. The impedance spectra were analyzed with lumped-element models. The impedance spectra of the scaffold can be embodied in equivalent circuit models composed of passive components of the circuit, i.e., resistors, inductors and capacitors. It represents the morphological, structural and chemical characteristics of the bone scaffold. The developed models describe the impedance characteristics of plant tissue. In this study, it was found that the ε′ and ε″ of scaffold composites exhibited up and down trends over frequencies for both X-band and Ku-band. The circuit models presented the lowest mean percentage errors of Z′ and Z″, i.e., 3.60% and 13.80%, respectively.

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The mechanical characterization of dioscorea alata and plectranthus rotundifolius starch-HA composite

2018-11 , N. A. F. Mohd Hori , Nashrul Fazli Mohd Nasir , Nasrul Amri Mohd Amin , Cheng Ee Meng , Mohd Shukry Abdul Majid , S. A. Rahman

The scaffolds made of starch-hydroxyapatite (HA) were fabricated by using solvent casting method and particulate leaching technique. The starches originated from Malaysian tubers which were Dioscorea alata (purple yam) and Plectranthus rotundifolius (Chinese potato). A composite were prepared by adding different weight of HA and of starch powder together with 20 ml of distilled water. The 50%, 60%, and 70% concentrations of starch-HA were prepared in this study. After the fabrication process, the effect of the starch-HA composites were investigated. The microstructures and the morphology of the composite scaffold were observed using SEM and the mechanical properties (Young’s modulus) of the scaffold is obtained by performing compressive test on the scaffolds. The results shows that the mechanical strength of Plectranthus rotundifolius is stronger compared to Dioscorea alata with the Young’s modulus of (70% starch in the composite) is 15.55 MPa for Dioscorea alata and 18.81 MPa for Plectranthus rotundifolius.

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Fabrication and characterization of three-dimensional porous cornstarch/n-HAp biocomposite scaffold

2020-12-01 , Beh C.Y. , Cheng Ee Meng , Nashrul Fazli Mohd Nasir , Mohd Shukry Abdul Majid , Mohd Roslan M.R. , You K.Y. , Khor Shing Fhan , Mohd Ridzuan Mohd Jamir

The aim of this study is to investigate the morphological, functional group, crystallinity and mechanical properties of a three-dimensional porous cornstarch/n-HAp (nano-hydroxyapatite) biocomposite scaffold. In this study, cornstarch/n-HAp scaffolds were fabricated using the solvent casting and particulate leaching technique. The porous cornstarch/n-HAp composites with various cornstarch contents (30, 40, 50, 60, 70, 80 and 90 wt%) were prepared and characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffractometer and compression test. The morphology of the scaffolds possessed macropores (200–600 Î¼m) and micropores (50–100 Î¼m) with a high interconnectivity. The porosity of the porous cornstarch/n-HAp scaffolds varied between 53 and 70% with compressive strength and compressive modulus of 2.03 and 8.27 MPa, respectively. The results suggested that highly porous cornstarch/n-HAp scaffold properties with adequate mechanical properties can be obtained for applications in bone tissue engineering.

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Publication

Lumped-element circuit modeling for composite scaffold with Nano-Hydroxyapatite and wangi rice starch

2023 , Xiao Jian Tan , Cheng Ee Meng , Nashrul Fazli Mohd Nasir , Mohd Shukry Abdul Majid , Mohd Ridzuan Mohd Jamir , Khor Shing Fhan , Kim Yee Lee , Kok Yeow You , Che Wan Sharifah Robiah Mohamad

Mechanistic studies of the interaction of electromagnetic (EM) fields with biomaterials has motivated a growing need for accurate models to describe the EM behavior of biomaterials exposed to these fields. In this paper, biodegradable bone scaffolds were fabricated using Wangi rice starch and nano-hydroxyapatite (nHA). The effects of porosity and composition on the fabricated scaffold were discussed via electrical impedance spectroscopy analysis. The fabricated scaffold was subjected to an electromagnetic field within the X-band and Ku-band (microwave spectrum) during impedance/dielectric measurement. The impedance spectra were analyzed with lumped-element models. The impedance spectra of the scaffold can be embodied in equivalent circuit models composed of passive components of the circuit, i.e., resistors, inductors and capacitors. It represents the morphological, structural and chemical characteristics of the bone scaffold. The developed models describe the impedance characteristics of plant tissue. In this study, it was found that the ε′ and ε″ of scaffold composites exhibited up and down trends over frequencies for both X-band and Ku-band. The circuit models presented the lowest mean percentage errors of Z′ and Z″, i.e., 3.60% and 13.80%, respectively.