Synthesis of zinc oxide nanoparticles via cellar spider extract for enhanced functional properties in antimicrobial activities
2024-06,
Jasni Mohamed Ismail,
Muhammad Nur Aiman Uda,
M. A. R. Irfan,
Mohd Khairul Rabani Hashim,
Zainal Abidin Arsat,
Uda Hashim,
Hafiza Shukor,
M. N. Afnan Uda,
Lokman Hakim Ibrahim,
Shahidah Arina Shamsuddin,
Nor Azizah Parmin,
Muzamir Isa,
Mohamad Zaim Mohamad Zain,
R. A. Ilyas,
Tijjani Adam
This study explores the green synthesis of zinc oxide nanoparticles (ZnO NPs) using cellar spider extracts as a sustainable alternative to traditional methods involving hazardous chemicals and radiation. The spider extracts effectively reduced zinc acetate dihydrate, yielding white precipitates indicative of ZnO NPs. Characterization through SEM revealed diverse morphologies, including spherical, rod-like, hexagonal, and uneven particles forming platelet-like aggregates. Further analyses, such as HPM, 3D nanoprofiler, and EDS, provided insights into size, shape, morphology, surface chemistry, thermal stability, and optical characteristics, quantifying the intended properties of the synthesized ZnO NPs. Antibacterial assays against E. coli and B. subtilis demonstrated significant antibacterial activity, affirming the nanoparticles' potential for antimicrobial applications. This green synthesis approach, validated through comprehensive characterization and quantitative measurements, offers a promising and environmentally friendly route for producing functional ZnO NPs.