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Robust Image Processing Framework for Intelligent Multi-Stage Malaria Parasite Recognition of Thick and Thin Smear Images

2023-02-01 , Aris T.A. , Aimi Salihah Abdul Nasir , Wan Azani Wan Mustafa , Mohd Yusoff Mashor , Haryanto E.V. , Mohamed Z.

Malaria is a pressing medical issue in tropical and subtropical regions. Currently, the manual microscopic examination remains the gold standard malaria diagnosis method. Nevertheless, this procedure required highly skilled lab technicians to prepare and examine the slides. Therefore, a framework encompassing image processing and machine learning is proposed due to inconsistencies in manual inspection, counting, and staging. Here, a standardized segmentation framework utilizing thresholding and clustering is developed to segment parasites’ stages of P. falciparum and P. vivax species. Moreover, a multi-stage classifier is designed for recognizing parasite species and staging in both species. Experimental results indicate the effectiveness of segmenting thick smear images based on Phansalkar thresholding garnered an accuracy of 99.86%. The employment of variance and new transferring process for the clustered members, enhanced k-means (EKM) clustering has successfully segmented all malaria stages with accuracy and an F1-score of 99.20% and 0.9033, respectively. In addition, the accuracies of parasite detection, species recognition, and staging obtained through a random forest (RF) accounted for 86.89%, 98.82%, and 90.78%, respectively, simultaneously. The proposed framework enables versatile malaria parasite detection and staging with an interactive result, paving the path for future improvements by utilizing the proposed framework on all others malaria species.

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Fast k-means clustering algorithm for malaria detection in thick blood smear

2020-11-09 , Aris T.A. , Aimi Salihah Abdul Nasir , Lim Chee Chin , Haryati Jaafar , Mohamed Z.

Lots of people all over the world is threaten by a popular blood infection illness that is called as malaria. According to this fact, immediate diagnosis tests are essential to avoid the malaria parasites from expanding in every part of the body. Malaria detection is based on parasitic count process on thick blood smear samples. Anyhow, this mechanism consist the chances of misinterpretation of parasites on behalf to human flaws. Thus, this research objective is to investigate the segmentation performance for improving malaria detection in thick blood smear images through fast k-means clustering algorithm on various color models. In this research, fast kmeans clustering is used because of its advantage which is no need to retrain cluster center that causes time taken to train the image cluster centers is reduce. Meanwhile, different color models have been utilized in order to identify the most relevant color model that obviously highlight the parasites. Five varied color models namely RGB, XYZ, HSV, YUV and CMY are selected and 15 color components namely R, G, B, X, Y, Z, H, S, V, Y, U, V, C, M and Y component have been derived with the aim to discover which color component is the topnotch for malaria parasites detection. In general, around 100 thick blood smear images have been tested in this study and the outcomes reveal that the best segmentation performance is segmentation through R component of RGB with 99.81% accuracy.