Shahidah Arina Shamsuddin
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Preferred name
Shahidah Arina Shamsuddin
Official Name
Shahidah Arina, Shamsuddin
Alternative Name
Shamsuddin, Shahidah Arina
Main Affiliation
Scopus Author ID
54785057000
Researcher ID
FWR-5498-2022

Research Output

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Analysis on silica and graphene nanomaterials obtained from rice straw for antimicrobial potential

2024-06 , Muhammad Nur Aiman Uda , N. H. A Jalil , Muhammad Firdaus Abdul Muttalib , Fahisal Abdullah , Uda Hashim , Subash Chandra Bose Gopinath , Shahidah Arina Shamsuddin , Nursakinah Abdul Karim , Ahmad Radi Wan Yaakub , Nur Hulwani Ibrahim , Tijjani Adam , Nor Azizah Parmin , Nadiya Akmal Baharum

This study focuses on the encapsulation of silica and graphene nanoparticles and their potential applications. The encapsulation enhances the properties and effectiveness of these nanoparticles, with silica providing stability and graphene contributing to high surface area and electrical conductivity. Characterization of silica-graphene nanoparticles was conducted using various techniques including High Power Microscope (HPM), Scanning Electron Microscope (SEM), Energy-dispersive X-ray spectroscopy (EDS), and 3D Nano Profiler. The antimicrobial activity of silica, graphene, and silica-graphene nanoparticles was evaluated using a disc diffusion assay against E. coli and B. subtilis at varying concentrations. Results showed significant antimicrobial activity, with the inhibition zone being directly proportional to the concentration. Silica-graphene nanoparticles demonstrated higher efficacy against E. coli compared to B. subtilis, attributed to differences in cell wall structure. Statistical analysis using ANOVA confirmed significant differences in antimicrobial activity among the tested components.

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Immunosensing prostate-specific antigen: Faradaic vs non-Faradaic electrochemical impedance spectroscopy analysis on interdigitated microelectrode device

2020-11-01 , Ibau, Conlathan , Mohd Khairuddin Md Arshad , Mohammad Nuzaihan Md Nor , Subash Chandra Bose Gopinath , Mohamad Faris Mohamad Fathil , Shahidah Arina Shamsuddin

This work explores Electrochemical Impedance Spectroscopy (EIS) detection for a highly-sensitive quantification of prostate-specific antigen (PSA) in Faradaic (f-EIS) and non-Faradaic modes (nf-EIS). Immobilization of monoclonal antibody specific to PSA (anti-PSA) was performed using 1-ethyl-3-dimethylaminopropylcarbodiimide hydrochloride and N-hydroxysuccinimide crosslinking agents in order to conjugate carboxylic (-COOH) terminated group of 16-Mercaptoundecanoic acid with amine (-NH3+) on anti-PSA epitope. This approach offers simple and efficient approach to form a strong, covalently bound thiol-gold (S–Au) for a reliable SAM layer formation. Studies on the topographic of pristine Au-IDE surface were performed by Scanning Electron Microscopy and Energy Dispersive X-ray Spectroscopy techniques, meanwhile a 3-dimensional optical surface profiler, Atomic Force Microscopy and X-ray Photoelectron Spectroscopy techniques were used to validate the successful functionalization steps on the sensor transducer surface. Detection of PSA in f-EIS mode was carried out by measuring the response in charge transfer resistance (Rct) and impedance change (Z), meanwhile in nf-EIS mode, the changes in device capacitance was monitored. In f-EIS mode, the sensor reveals a logarithmic detection of PSA in a range of 100 ng/ml down to 0.01 ng/ml in Phosphate Buffered Saline with a recorded sensitivity of 2.412 kΩ/log10 ([PSA] ng/ml) and the limit of detection (LOD) down to 0.01 ng/ml. The nf-EIS detection mode yields a logarithmic detection range of 5000 ng/ml down to 0.5 ng/ml, with a sensitivity of 8.570 nF/log10 ([PSA] ng/ml) and an LOD of 0.5 ng/ml. The developed bio-assay yields great device stability, specificity to PSA and repeatability of detection that would pave its way for the future development into portable lab-on-chip bio-sensing system.

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Design and Development of Single-Handed Kitchenware for Individuals with Hand Disabilities

2025-06-10 , Muhammad Ikman Ishak , Muhamad Ikhmal Alif Abdullah , Ahmad Ramli Rashidi , Shahidah Arina Shamsuddin , Normah Kassim , Wan Nur A'tiqah Wan Draman , Noor Diyana Dahlan

Traditional kitchen equipment often poses significant challenges and risks for individuals with hand disabilities or impairments, increasing the likelihood of burns, cuts, and other injuries during food preparation. For people with physical disabilities or injuries affecting one hand, performing routine cooking tasks can be difficult and time-consuming. The reliance on traditional two-handed kitchen tools limits their ability to cook independently. This study aimed to design and develop innovative single-handed kitchenware equipped with multiple meal preparation tools and ergonomic features to enhance the cooking experience for individuals with hand disabilities. A combination of primary and secondary data was gathered through observations, interviews, and a review of journal articles. The research process involved concept development, three-dimensional modeling and analysis, and usability testing. The results demonstrated that the proposed single-handed kitchenware, made from PLA material, effectively integrates essential features such as a peeler, grater, cutting board, stopping rods, and a storage compartment into a single unit. While the design shows promise in improving meal preparation processes, achieving cutting and peeling speeds that are 51% and 65% faster, respectively, compared to conventional tools, further refinements are recommended. For instance, improvements in the grating function could optimize its overall performance and usability, particularly for individuals with hand impairments.

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Cost-effective fabrication of polydimethylsiloxane (PDMS) microfluidics for point-of-care application

2024-06 , Adilah Ayoib , Noor Amalina Aini Abdul Karim , Uda Hashim , Shahidah Arina Shamsuddin , Siti Fatimah Abd Rahman , Mohamad Faris Mohamad Fathil , Nor Azizah Parmin

Microfluidics fabrication pertains to the construction of small-scale devices and systems that manipulate and control small volumes of fluids. This process involves precise engineering and manufacturing procedures aimed at designing and producing these devices, which find applications in healthcare, environmental monitoring, and chemical analysis. The present study showcases an inexpensive approach to fabricate microfluidics channels using PDMS biopolymer and soft lithography technique to achieve laminar fluid flow. Initially, a robust and adhesive mold was created by fabricating a master template using several layers of SU-8 5 and SU-8 2015 negative photoresists. Subsequently, PDMS microfluidics channels were replicated and sealed onto a glass substrate through plasma bonding treatment. High-power microscopy images and profilometer analyses demonstrated successful fabrication with minimal deviation from the initial designs and the fabricated devices (less than 0.07 mm, less than 0.6°). Both the SU-8 master template and PDMS replicate displayed average microchannel height values and surface roughness of 100 μm and 0.26 μm or lower, respectively. Additionally, the fluid test confirmed laminar flow without any leakage post plasma oxidation, indicating the completion of an efficient and cost-effective fabrication process.

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Study on the effects of anodizing voltage to the AAO thin film dimensional properties synthesized by single step anodization method

2021-05-03 , Shahidah Arina Shamsuddin , Mohd Nazree Derman , Uda Hashim , Muhammad Faheem Mohd. Tahir

Anodic aluminium oxide (AAO) thin film electrodes were synthesized by using a single step anodizing method in 15 °C of 0.3 M oxalic acid at five different anodizing voltage ranging from 20 V to 60 V, respectively. The effect of anodizing voltage to the AAO dimensional properties were about to be investigated. Morphological observations were all done by FESEM where the measurements and calculation were made by using ImageJ and formulas. To ensure that the pore sizes were totally depended on the anodizing voltage, etching process were done at constant duration for all samples. The correlation between all AAO dimensional properties like pores size, interpore distance, wall thickness, pore density, percentage of porosity and nanoporous oxide thickness were presented in a linear graph.

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Aluminium interdigitated electrode with 5.0 μm gap for electrolytic scooting

2024-06 , Uda Hashim , Muhammad Nur Aiman Uda , Tijjani Adam , Asral Bahari Jambek , Ismail Saad , Nor Azizah Parmin , Shahidah Arina Shamsuddin , Nursakinah Abdul Karim , G. Yashni , Nur Hulwani Ibrahim , N. Parimon , M. F. H. Rani

The goal of the research project is to design, fabricate, and characterize an extremely sensitive biosensor for use in healthcare. Using AutoCAD software, a novel IDE pattern with a 5 μm finger gap was created. Conventional photolithography and regular CMOS technology were used in the fabrication process. A 3D nano profiler, scanning electron microscopy (SEM), high-power microscopy (HPM), and low-power microscopy (LPM) were used to physically characterize the manufactured IDE. Chemical testing was done using several pH buffer solutions, and electrical validation was performed using I-V measurements. The Al IDE was produced, with a tolerance of 0.1 μm between the fabricated IDEs and the design mask. Electrical measurements verified the flawless fabrication of the IDE, and the device's repeatability was validated by the outcomes of comparable IDE samples. For each pH buffer solution, a modest additional volume of 2 μl was used to quantitatively detect slight current fluctuations in the microampere range. Through pH calibration for advanced applications in the realm of chemical sensors using an amperometric method, this research study has verified the chemical behavior of the IDE.

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Surface characterization study of nanoporous anodic aluminium oxide thin film synthesized by single-step anodization

2021-05-03 , Shahidah Arina Shamsuddin , Mohd Nazree Derman , Uda Hashim , Ismail J. , Muhammad Faheem Mohd. Tahir

Nanoporous anodic aluminium oxide (AAO) thin film electrodes were prepared by using a single step anodization method in 0.3 M oxalic acid at 40 V for 1 h. Electrolyte temperature was controlled and maintained at 15 °C by using ice water bath. After anodized, AAO surfaces were etched by using 5% phosphoric acid (H3PO4) solution at 30 °C to remove the AAO top rough surfaces and widening the pores. Effect of different etching duration to the pore widening was investigated at 10, 20 and 30 minutes, respectively. Regularity of the pores arrangements before and after etching were analysed by fast fourier transform (FFT) profile images that were generated from FESEM images. From observation, well ordered nanoporous structures were successfully revealed after top rough surfaces were removed by etching. Pores sizes were also found to be increased with the increasing of etching duration. Further investigations were done by x-ray diffraction (XRD) analysis and fourier transform infra-red spectroscopy (FTIR) to characterize and find out the crystallinity properties and functionalities of AAO thin film electrode surfaces.

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Publication

Cost-Effective Fabrication of Polydimethylsiloxane (PDMS) Microfluidics for Point-of-Care Application

2024-06-01 , Adilah Ayoib , Karim N.A.A.A. , Uda Hashim , Shahidah Arina Shamsuddin , Abd Rahman S.F. , Mohamad Faris Mohamad Fathil , Nor Azizah Parmin

Microfluidics fabrication pertains to the construction of small-scale devices and systems that manipulate and control small volumes of fluids. This process involves precise engineering and manufacturing procedures aimed at designing and producing these devices, which find applications in healthcare, environmental monitoring, and chemical analysis. The present study showcases an inexpensive approach to fabricate microfluidics channels using PDMS biopolymer and soft lithography technique to achieve laminar fluid flow. Initially, a robust and adhesive mold was created by fabricating a master template using several layers of SU-8 5 and SU-8 2015 negative photoresists. Subsequently, PDMS microfluidics channels were replicated and sealed onto a glass substrate through plasma bonding treatment. High-power microscopy images and profilometer analyses demonstrated successful fabrication with minimal deviation from the initial designs and the fabricated devices (less than 0.07 mm, less than 0.6°). Both the SU-8 master template and PDMS replicate displayed average microchannel height values and surface roughness of 100 μm and 0.26 µm or lower, respectively. Additionally, the fluid test confirmed laminar flow without any leakage post plasma oxidation, indicating the completion of an efficient and cost-effective fabrication process.

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Publication

Analysis on Silica and Graphene Nanomaterials Obtained From Rice Straw for Antimicrobial Potential

2024-06-12 , Muhammad Nur Aiman Uda , A Jalil N.H. , Muhammad Firdaus Abdul Muttalib , Fadhilnor Abdullah , Uda Hashim , Subash Chandra Bose Gopinath , Afnan Uda M.N. , Shahidah Arina Shamsuddin , Norizah Abd Karim , Ahmad Radi Wan Yaakub , Ibrahim N.H. , Tijjani Adam , Nor Azizah Parmin , Baharum N.A.

This study focuses on the encapsulation of silica and graphene nanoparticles and their potential applications. The encapsulation enhances the properties and effectiveness of these nanoparticles, with silica providing stability and graphene contributing to high surface area and electrical conductivity. Characterization of silica-graphene nanoparticles was conducted using various techniques including High Power Microscope (HPM), Scanning Electron Microscope (SEM), Energy-dispersive X-ray spectroscopy (EDS), and 3D Nano Profiler. The antimicrobial activity of silica, graphene, and silica-graphene nanoparticles was evaluated using a disc diffusion assay against E. coli and B. subtilis at varying concentrations. Results showed significant antimicrobial activity, with the inhibition zone being directly proportional to the concentration. Silica-graphene nanoparticles demonstrated higher efficacy against E. coli compared to B. subtilis, attributed to differences in cell wall structure. Statistical analysis using ANOVA confirmed significant differences in antimicrobial activity among the tested components.

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Publication

Aluminium Interdigitated Electrode with 5.0 µm Gap for Electrolytic Scooting

2024-06-01 , Afnan Uda M.N. , Uda Hashim , Asral Bahari Jambek , Tijjani Adam , Saad I. , Muhammad Nur Aiman Uda , Nor Azizah Parmin , Shahidah Arina Shamsuddin , Norizah Abd Karim , Yashni G. , Ibrahim N.H. , Parimon N. , Rani M.F.H.

The goal of the research project is to design, fabricate, and characterize an extremely sensitive biosensor for use in healthcare. Using AutoCAD software, a novel IDE pattern with a 5 µm finger gap was created. Conventional photolithography and regular CMOS technology were used in the fabrication process. A 3D nano profiler, scanning electron microscopy (SEM), high-power microscopy (HPM), and low-power microscopy (LPM) were used to physically characterize the manufactured IDE. Chemical testing was done using several pH buffer solutions, and electrical validation was performed using I-V measurements. The Al IDE was produced, with a tolerance of 0.1 µm between the fabricated IDEs and the design mask. Electrical measurements verified the flawless fabrication of the IDE, and the device's repeatability was validated by the outcomes of comparable IDE samples. For each pH buffer solution, a modest additional volume of 2 µl was used to quantitatively detect slight current fluctuations in the microampere range. Through pH calibration for advanced applications in the realm of chemical sensors using an amperometric method, this research study has verified the chemical behavior of the IDE.

View