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  • Publication
    Miniaturized Electrochemical Device for In-Situ Monitoring of Glucose, Lactate, Dissolved Oxygen, PH, and Temperature in Yeast Culture
    ( 2021-06-20) ;
    Espinar P.L.
    ;
    Ceyssens F.
    ;
    Taurino I.
    ;
    Kraft M.
    This paper presents the integration on a single chip of multiple electrochemical sensors based on amperometric and potentiometric techniques, as well as of a physical sensor. The prototype comprises six sensors for in-situ monitoring of important parameters of a bioprocess; glucose, lactate, pH, cell density, dissolved oxygen, and temperature. All sensor elements have been calibrated and showed acceptable detection performance. We also demonstrate a preliminary experiment for in-situ monitoring in a yeast culture to better understand the response of the proposed microsensors towards yeast fermentations application.
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