Muhammad Nur Aiman Uda
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Preferred name
Muhammad Nur Aiman Uda
Official Name
Muhammad Nur Aiman, Uda
Alternative Name
Uda, M. N.A.
Aiman Uda, Muhammad Nur
Uda, M. N.A.
Main Affiliation
Scopus Author ID
55984680000
Researcher ID
V-7751-2019

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  • Publication
    Label-free aptamer based biosensor for heavy metal detection
    ( 2020-11-02)
    Muhammad Nur Aiman Uda
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Muhammad Nur Afnan Uda
    ;
    Nor Azizah Parmin
    ;
    Isa A.M.
    Heavy metal contamination such as arsenic becomes serious threat to the health and environment of many millions in a worldwide. Arsenic contamination especially in paddy field has driven to the accumulation of As in paddy soils and possibly have adverse effects on rice products. To assess the level of severity of arsenic in paddy field is a major constraint at early stages. In the past, quantification of concentration of arsenic has been as difficult as reducing it. Thus label free Aptamer based biosensor is the most reliable sensor recently due to the advantages for the sensitive and selective detection towards detecting arsenic. Finally, this paper will discuss the current outcomes in arsenic detection using Aptasensor with sensing element formatting in enhancing the sensor signal for detection.
  • Publication
    Development of Voltage Amplifier Electronic Reader for Multiplex Detection of Two Electrode Electrical Biosensors
    ( 2020-03-18)
    Muhammad Nur Afnan Uda
    ;
    Asral Bahari Jambek
    ;
    Uda Hashim
    ;
    Muhammad Nur Aiman Uda
    Amperometric electrical biosensors have small current variations at nano to micro range. There are limited number of electrical based two electrode electronic readers for biosensors are commercial available because of the amplification and noise issues at nano to micro ampere current range. The electronic reader focused on design a voltage amplifier circuit to capture and amplify three different range of current as nano, micro and mili ampere and convert it to detectable voltage range as an output voltage signal. Current input as nano, micro and mili current were flown through 10 K , 10 and 10 m resistors, respectively to convert different current inputs to the similar range in micro voltage. Then, MAX 4238 op-amp IC was used to amplify micro voltage to mili voltage. Arduino Uno circuit was act as the process and control circuit to read the output voltage from the amplifier circuit. Arduino Uno circuit will convert analog signal to digital signal and then the output voltage value is display in the LCD screen. The Proteus 8 Pro software was used to design, simulate and calibrate the amplifier circuit and Arduino Uno circuit. While, Arduino software was used to create a programming code and to upload in Arduino Uno circuit. Start your abstract here.
  • Publication
    Titanium dioxide (TiO2) nanoparticles on aluminium interdigitated electrodes (Al IDE) for sensitive pH detection
    ( 2020-11-02)
    Uda M.N.A.
    ;
    Asral Bahari Jambek
    ;
    Uda Hashim
    ;
    Muhammad Nur Aiman Uda
    Titanium dioxide (TiO2) nanoparticles based Aluminium Interdigitated Electrode (Al IDE) was tested as pH electrodes and measured quantitatively. TiO2 nanoparticle was synthesized using sol-gel method with monoethanolamine (MEA) as a catalyst. The mixing of titanium butoxide as a precursor, ethanol as a solvent and MEA as stabilizer were stirred using magnetic stirrer under ambient temperature. Al IDE were fabricated by conventional photolithography method. TiO2 solution prepared then was deposited on Al IDE using spin-coater and the coated device were annealed at 400°C. Deposition of TiO2 solution on the fabricated Al IDE forms a sensor that promising for development of TiO2 nanoparticle based biosensors. The surface morphologies structural properties were studied using Scanning Electron Microscopy (SEM). The small amount of current measurement of this device towards hydrogen and hydroxide ions was measured by Keithley 2450 pico ammeter.
  • Publication
    Nano-micro-mili Current to Mili Voltage Amplifier for Amperometric Electrical Biosensors
    ( 2020-03-18)
    Muhammad Nur Afnan Uda
    ;
    Parmin N.A.
    ;
    Asral Bahari Jambek
    ;
    Uda Hashim
    ;
    Muhammad Nur Aiman Uda
    ;
    Shaharuddin S.N.A.
    ;
    Adam H.
    Amplification of nano and mircoampere electrical signal to the detectable range is essential in the biosensor field. This research is mainly focused on design an amplifier circuit to capture and amplify three different range of current as nano, micro and mili ampere and convert it to detectable voltage range as an output signal to the processing circuit. The Proteus 8 Pro software was used to design, simulate and calibrate the amplifier circuit. Firstly, current input as mili, micro and nano current were flown through 0.1 m, 10 and 10 K resistors, respectively to convert different current inputs to the similar range in micro voltage. The MAX 4238 opamp IC was used to amplify micro voltage to mili voltage. LM 358 dual operational amplifier was used to supply virtual ground to MAX 4238 amplifier. The amplified output voltage of three different current inputs as nano, micro and mili were nearly equal to theoretical outputs.
  • Publication
    Morphological Analysis of Fabricated 5.0 μM Interdigitated Electrode (IDE)
    ( 2021-12-14)
    Muhammad Nur Aiman Uda
    ;
    Subash Chandra Bose Gopinath
    ;
    Uda Hashim
    ;
    Muhammad Nur Afnan Uda
    ;
    Nor Azizah Parmin
    ;
    Halim N.H.
    ;
    Hashim M.K.R.
    ;
    Anbu P.
    The aim of this research is to study the morphological analysis of fabricated Interdigitated Electrode (IDE). This device electrode was physically characterized using 3D nano profiler, scanning electrode microscope (SEM), Energy-dispersive X-ray spectroscopy (EDX) and Atomic Force Microscope (AFM). Based on this analysis, IDE pattern was analyzed thoroughly based on the IDE pattern specifications with 5 μM finger gap and this research significantly will stand as a platform quantify the biomolecules in further analysis.
  • Publication
    Analysis on silica and graphene nanomaterials obtained from rice straw for antimicrobial potential
    ( 2024-06)
    Muhammad Nur Aiman Uda
    ;
    N. H. A Jalil
    ;
    Muhammad Firdaus Abdul Muttalib
    ;
    Fahisal Abdullah
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Shahidah Arina Shamsuddin
    ;
    Nursakinah Abdul Karim
    ;
    Ahmad Radi Wan Yaakub
    ;
    Nur Hulwani Ibrahim
    ;
    Tijjani Adam
    ;
    Nor Azizah Parmin
    ;
    Nadiya Akmal Baharum
    This study focuses on the encapsulation of silica and graphene nanoparticles and their potential applications. The encapsulation enhances the properties and effectiveness of these nanoparticles, with silica providing stability and graphene contributing to high surface area and electrical conductivity. Characterization of silica-graphene nanoparticles was conducted using various techniques including High Power Microscope (HPM), Scanning Electron Microscope (SEM), Energy-dispersive X-ray spectroscopy (EDS), and 3D Nano Profiler. The antimicrobial activity of silica, graphene, and silica-graphene nanoparticles was evaluated using a disc diffusion assay against E. coli and B. subtilis at varying concentrations. Results showed significant antimicrobial activity, with the inhibition zone being directly proportional to the concentration. Silica-graphene nanoparticles demonstrated higher efficacy against E. coli compared to B. subtilis, attributed to differences in cell wall structure. Statistical analysis using ANOVA confirmed significant differences in antimicrobial activity among the tested components.
  • Publication
    Facile electrical DNA genosensor for human papillomavirus (HPV 58) for early detection of cervical cancer
    ( 2023-07)
    F. Nadhirah Jaapar
    ;
    Nor Azizah Parmin
    ;
    Nur Hamidah Abdul Halim
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Ruslinda A. Rahim
    ;
    Sh. Nadzirah
    ;
    Voon Chun Hong
    ;
    Muhammad Nur Aiman Uda
    ;
    Wei Chern Ang
    ;
    Iffah Izzati Zakaria
    ;
    Zulida Rejali
    ;
    Amilia Afzan
    ;
    Azrul Azlan Hamzah
    ;
    Chang Fu Dee
    ;
    F. Syakirah Halim
    For decades, a Pap smear test has been applied as a conventional method in detecting Human Papillomavirus caused cervical cancer. False-positive results were also recorded while using it as conventional method. Current biosensor such as Hybrid (II) Capture resulted in higher time consumption and cost. s Meanwhile, in this study we provided facile, mini, rapid, highly sensitive, eco-friendly, and cost-effective sensing system focusing on HPV strain 58 (HPV58) in a nano-size lab-on-chip technology genosensor. 30-mer of virus ssDNA designed and analyzed as a probe via bioinformatics tools such as GenBank, Basic Local Alignment Searching Tools (BLAST) and ClustalW. Nanotechnology-developed colloidal Gold-nanoparticles (AuNPs) are used in the biosensor fabrication to produce high stability and electron efficient transmission during electrical measurement. AuNPs-APTES modified on active sites of IDEs, followed by immobilization of specific probe ssDNA for HPV 58. Hydrogen binding during hybridization with its target produce electrical signals measured by KEITHLEY 2450 (Source Meter). The genosensor validated with different types of targets such as complimentary, non-complementary and single mismatch oligonucleotides. The serial dilution of target concentration has been experimented triplicate (n=3) range from 1fM to 10μM. The slope of calibration curve resulted 2.389E-0 AM-1 with regression coefficient (R2) = 0.97535.
  • Publication
    Effect of Potassium Permanganate and Zeolite on Shelf Life and Quality of Musa Acuminata
    ( 2020-07-09)
    Yi Yin C.
    ;
    Maisara Azad Mat Akhir
    ;
    Muhammad Nur Aiman Uda
    ;
    Nuradibah Mohd Amer
    This paper study the effect of ethylene scavenger treatments in different quantity (T0: 0g, T1: 1g, T2: 3g, T3: 5g and T4: 10g per sachet) and types of packaging (T5: non-perforated and T6: perforated packaging) on Musa Acuminata to its shelf life and physicochemical quality. Potassium permanganate (KMnO4) and zeolite were used as ethylene absorbent which stored together with the bananas under uniform atmospheric condition at temperature of 25-28°C and 85-95% of relative humidity (RH). Physicochemical analysis (e.g. weight loss, peel colour changes, firmness, total soluble solid content and titratable acidity) were performed to evaluate the effectiveness of each treatments throughout its storage period. Results showed that treatment with higher quantity of KMnO4-zeolite (T4: 10g) shows reduction and retardation in percent weight loss (9.62%), peel colour changes, firmness changes (28.2%), total soluble solid (TSS) (12.1% Brix), titratable acidity (TA) (0.084% malic acid) and also greater storability of banana. Therefore, postharvest losses can be reduced by the mentioned treatment and it can be implemented in postharvest industries for extending the shelf life of banana effectively.
  • Publication
    Distinct Detection of Ganoderma Boninense On Metal Oxides-Gold Nanoparticle Composite Deposited Interdigitated Electrode DNA sensor
    ( 2021-12-14)
    Thivina V.
    ;
    Uda Hashim
    ;
    Subash Chandra Bose Gopinath
    ;
    Adilah Ayoib
    ;
    Nordin N.K.S.
    ;
    Muhammad Nur Aiman Uda
    ;
    Muhammad Nur Afnan Uda
    Oil palms suffer severe losses due to Ganoderma boninense infection that causes Basal Stem Rot (BSR). The available detection measuring the severity of BSR disease have not proved satisfactory output. Due to the influence of oil palm industry in country's economy, effective and efficient means of diagnostic measure is mandatory. Among the available diagnostic tools, biosensors were redeemed to yield the most rapid and selective results. To overcome the current issues, herein Interdigitated Electrode (IDE) electrochemical DNA biosensor to detect Ganoderma boninense was successfully designed and fabricated by thermal deposition. Lift-off photolithography fabrication process was applied followed by the surface chemical functionalization via seed deposition. Zinc Oxide (ZnO) and Titanium Dioxide (TiO2) were overlaid and the functionalized metal oxides IDE surfaces were used to detect DNA sequence complementation from Ganoderma boninense. Furthermore, gold nanoparticles were doped to increase the surface to volume ratio and enhance biocompatibility. Characterizations were made by validating the sensor's topology characteristics and electrical characteristics. From the results recorded, it has been justified that IDE with ZnO doped with gold nanoparticles surface serves as an excellent DNA sensor for the detection of Ganoderma boninense with a remarkable current of 290 nA and 176 nA for immobilization and hybridization respectively.
  • Publication
    Production and characterization of silica nanoparticles from fly ash: conversion of agro-waste into resource
    ( 2021-01-01)
    Muhammad Nur Aiman Uda
    ;
    Subash Chandra Bose Gopinath
    ;
    Uda Hashim
    ;
    Halim N.H.
    ;
    Parmin N.A.
    ;
    Muhammad Nur Afnan Uda
    ;
    Anbu P.
    A chemical method to synthesize amorphous silica nanoparticles from the incinerated paddy straw has been introduced. The synthesis was conducted through the hydrolysis by alkaline-acidic treatments. As a result, silica particles produced with the sizes were ranging at 60–90 nm, determined by high-resolution microscopy. The crystallinity was confirmed by surface area electron diffraction. Apart from that, chemical and diffraction analyses for both rice straw ash and synthesized silica nanoparticles were conducted by X-ray diffraction and Fourier-transform infrared spectroscopy. The percentage of silica from the incinerated straw was calculated to be 28.3. The prominent surface chemical bonding on the generated silica nanoparticles was with Si–O–Si, stretch of Si–O and symmetric Si–O bonds at peaks of 1090, 471, and 780 cm−1, respectively. To confirm the impurities of the elements in the produced silica, were analyzed using X-ray photoelectron spectroscopy and energy dispersive X-ray spectroscopy. The stability of silica nanoparticles was investigated using thermogravimetric analysis and zeta potential. The measured size from zeta potential analysis was 411.3–493 nm and the stability of mass reduction was located at 200 °C with final amount of mass reduced ∼88% and an average polydispersity Index was 0.195–0.224.