Osteogenesis Imperfecta (OI) is a disease that affect the bone in terms of deformity and brittleness. It is known that after certain deformation angles, OI bone cannot sustain the excessive stress that resulting to bone fracture. Although several studies have been undertaken to analyse the fracture prediction on OI bone due to deformity angles using finite element analysis, however none of them has validated experimentally. Hence, the main objective of this study was to investigate the validity of finite element analysis in predicting the fracture risk of OI-affected femur. For experimental works, the bone specimens were prepared using polylactic acid material through Fuse Deposition Material method at 15°, 20° and 25°deformation angles. Findings of this study show a promising result as the deformation response for the FEA was agreed to experimental result. Hence, it proves that prediction of finite element analysis on bone fracture risk of OI is acceptable. This study also found that femur bone with 25° deformation angle tend to fracture under minimum load. Therefore, patients that have femur bone at 25°deformation angles should be advised to undergo surgical intervention.
