The key advantages of 3D printing are its capability to produce complex structures and rapid prototyping. This has contributed to the development of modern material processing methods over the past years for industrial tasks and needs. However, the development of biodegradable feedstock for 3D printing filament and enhanced natural fiber as reinforcement filler to improve mechanical properties and biodegradation is still not fully explored. Also, there have been alarming concerns around the world about the use of non-biodegradable resources during 3D printing that could threaten the sustainable environment. This review discusses the types of biodegradable polymers, natural fibers with their properties and applications, the development method for non-biodegradable and biodegradable polymer composites obtained through fused filament fabrication (FFF). Finally, the challenges and future opportunities associated with 3D printing feedstock of biodegradable polymer composites are reviewed and analyzed.